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NBoc-DMT

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NBoc-DMT
Clinical data
Other namesNB-DMT; DMT-BOC; N′-t-BOC-DMT; N′-tert-Butoxycarbonyl-N,N-dimethyltryptamine
Drug classSerotonergic psychedelic; Hallucinogen; Serotonin receptor agonist; Serotonin 5-HT2A receptor agonist
Legal status
Legal status
  • Illegal in Russia
Identifiers
  • tert-butyl 3-[2-(dimethylamino)ethyl]indole-1-carboxylate
PubChem CID
Chemical and physical data
FormulaC17H24N2O2
Molar mass288.391 g·mol−1
3D model (JSmol)
  • CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)CCN(C)C
  • InChI=1S/C17H24N2O2/c1-17(2,3)21-16(20)19-12-13(10-11-18(4)5)14-8-6-7-9-15(14)19/h6-9,12H,10-11H2,1-5H3
  • Key:IKVMWFRRDDILJA-UHFFFAOYSA-N

NBoc-DMT, or NB-DMT, also known as N1-tert-butoxycarbonyl-N,N-dimethyltryptamine, is a serotonergic psychedelic of the tryptamine family.[1][2] It is a novel designer and recreational drug and is a synthetic modification of dimethyltryptamine (DMT) with an N′-tert-butyloxycarbonyl (NBoc) group.[1][2] NB-DMT is said to be a "prodrug" of DMT that decomposes into DMT when the compound is heated (e.g., with smoking or vaping),[1] and may also be useful as an orally active prodrug of DMT, unlike DMT itself which is inactive when taken orally.[3][4] It has been claimed to have about 25% of the potency of DMT by weight.[1] The drug was first detected as a designer drug being sold online by February 2024.[1] NB-DMT is a Schedule I controlled substance in Russia.[1] A number of other NBoc designer drugs have also been encountered.[1][5]

See also

[edit]

References

[edit]
  1. ^ a b c d e f g "DMT BOC (NB-DMT)". АИПСИН (AIPSIN) (in Russian). Retrieved 23 January 2025.
  2. ^ a b "Tert-butyl 3-[2-(dimethylamino)ethyl]indole-1-carboxylate". PubChem. U.S. National Library of Medicine. Retrieved 23 January 2025.
  3. ^ US 2024/0116870, Alexander M, Duncton J, Clark S, "N,N-dimethyltryptamine and related psychedelics and uses thereof.", published 11 April 2024, assigned to Terran Biosciences Inc. 
  4. ^ WO 2024/121253, Buchner M, "Novel N,N-Dimethyltryptamine (DMT) derivatives and uses thereof.", published 13 June 2024, assigned to Mihkal GmbH 
  5. ^ Johnson CS, Bogun B (2019). "Chemical camouflage: illicit drug concealment using di-tert-butyldicarbonate". Australian Journal of Forensic Sciences. 51: S217 – S219. doi:10.1080/00450618.2019.1569135. S2CID 86747489.


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