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Eticyclidine

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Eticyclidine
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • N-Ethyl-1-phenylcyclohexylamine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H21N
Molar mass203.329 g·mol−1
3D model (JSmol)
  • CCNC1(CCCCC1)C2=CC=CC=C2
  • InChI=1S/C14H21N/c1-2-15-14(11-7-4-8-12-14)13-9-5-3-6-10-13/h3,5-6,9-10,15H,2,4,7-8,11-12H2,1H3 checkY
  • Key:IFYLVUHLOOCYBG-UHFFFAOYSA-N checkY
  (verify)

Eticyclidine (PCE, CI-400) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400,[2] but research into PCE was not continued after the development of ketamine, a similar drug with more favourable properties.[3] Due to its similarity in effects to PCP, PCE was placed into the Schedule 1 list of illegal drugs in the 1970s, although it was only briefly abused in the 1970s and 1980s and is now little known.

See also

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References

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  1. ^ Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.
  2. ^ Levy L, Cameron DE, Aitken RC (March 1960). "Observation on two psychotomimetic drugs of piperidine derivation--CI 395 (sernyl) and CI 400". The American Journal of Psychiatry. 116 (9): 843–4. doi:10.1176/ajp.116.9.843. PMID 14416411.
  3. ^ Kalir A, Edery H, Pelah Z, Balderman D, Porath G (May 1969). "1-Phenycycloalkylamine derivatives. II. Synthesis and pharmacological activity". Journal of Medicinal Chemistry. 12 (3): 473–7. doi:10.1021/jm00303a030. PMID 4977945.


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