User:Pthoman/Rheumatoid arthritis

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Risk factors[edit]

RA is a systemic (whole body) autoimmune disease. Some genetic and environmental factors affect the risk for RA.

Vitamin D Deficiency

There are claims that patients that have lower vitamin D levels by 8-10 ng/mL are at risk for rheumatoid arthritis. ^[1]

Prevention[edit]

There is no known prevention for the condition other than the reduction of risk factors.

Supplementation

Evidence suggests that increasing vitamin D levels to the range of 40–60 ng/mL could reduce the risk of rheumatoid arthritis.^[2]

References

^ Giannini, Sandro; Giusti, Andrea; Minisola, Salvatore; Napoli, Nicola; Passeri, Giovanni; Rossini, Maurizio; Sinigaglia, Luigi (2022-01). "The Immunologic Profile of Vitamin D and Its Role in Different Immune-Mediated Diseases: An Expert Opinion". Nutrients. 14 (3): 473. doi:10.3390/nu14030473. ISSN 2072-6643. PMC 8838062. PMID 35276834. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
^ Charoenngam, Nipith; Holick, Michael F. (2020-07). "Immunologic Effects of Vitamin D on Human Health and Disease". Nutrients. 12 (7): 2097. doi:10.3390/nu12072097. ISSN 2072-6643. PMC 7400911. PMID 32679784. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)

[1] Giannini, Sandro; Giusti, Andrea; Minisola, Salvatore; Napoli, Nicola; Passeri, Giovanni; Rossini, Maurizio; Sinigaglia, Luigi (2022-01). "The Immunologic Profile of Vitamin D and Its Role in Different Immune-Mediated Diseases: An Expert Opinion". Nutrients. 14 (3): 473. doi:10.3390/nu14030473. ISSN 2072-6643. PMC 8838062. PMID 35276834. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)

[2] Charoenngam, Nipith; Holick, Michael F. (2020-07). "Immunologic Effects of Vitamin D on Human Health and Disease". Nutrients. 12 (7): 2097. doi:10.3390/nu12072097. ISSN 2072-6643. PMC 7400911. PMID 32679784. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)

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