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Urothelial papilloma

From Wikipedia, the free encyclopedia

A urothelial papilloma is a rare, noncancerous tumor found within the urinary tract.

Clinical Presentation

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The most common presenting symptom is hematuria (blood in urine). The average age at which it occurs is 46 years old.

Morphology and Histology

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The tumor is made of a fibrovascular core covered by seemingly normal urothelium tissue. Under microscope, papillary (finger-like) fronds can be seen that feature occasional branching, but no fusion.

Genetic Associations

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The tumors are diploid (contain two sets of chromosomes). They commonly show FGFR3 mutations.[1]

References

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  1. ^ "Pathology of Urinary Bladder Urothelial Papilloma: Definition, Clinical Features and Imaging, Gross and Microscopic Findings". 2023-12-19. {{cite journal}}: Cite journal requires |journal= (help)