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Medical textiles

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Health workers in PPE kits

Medical textiles are numerous fiber-based materials intended for medical purposes. Medical textile is a sector of technical textiles that emphasizes fiber-based products used in health care applications such as prevention, care, and hygiene.

The spectrum of applications of medical textiles ranges from simple cotton bandages to advanced tissue engineering.[1] Common examples of products made from medical textiles include dressings, implants, surgical sutures, certain medical devices, healthcare textiles, diapers, menstrual pads, wipes, and barrier fabrics.[2]

Medical textiles include many fiber types, yarns, fabrics, non-woven materials, woven, braided, as well as knitted fabrics.[3] Physical and chemical alterations of fiber architectures, the use of functional finishes, and the production of stimuli-sensitive materials are major approaches for developing innovative medical textiles.[2]

Advances in textile manufacturing and medical technologies have made medical healthcare an important industry in textiles.[2] Textiles are used in the production of a variety of medical devices, including replacements for damaged, injured, or non-functioning organs.[4] The manufacture of medical textiles is a growing sector. There are many reasons for its growth, such as new technology in both textiles and medicine; ageing populations; growing populations; changes in lifestyles; and longer life expectancies.[5]: 136  Additionally, the COVID-19 pandemic generated higher demand for certain medical textile applications [such as PPE, medical gowns and face masks], and there were shortages worldwide.[6][7][8] Even China, the world's largest manufacturer of such applications, has struggled to keep up with demand.[9]

History

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Achilles bandaging Patroclus. Tondo of an Attic red-figure kylix, ca. 500 BC, from Vulci.
Copper engraving of Doctor Schnabel (i.e., Dr. Beak), a plague doctor in seventeenth-century Rome, circa 1656

Natural fibers have been used in medical applications since ancient times.[10]: 1, 2  The use of splints, bandages, and gauges is very old.[11] An ancient Sanskrit text on medicine and surgery, the Sushruta Samhita, categorises Kausheya under the "articles of bandaging."[12] The concept of personal protective equipment (PPE) for medical practitioners dates all the way back to the 17th century. Plague doctor costumes were intended to protect plague doctors from the disease during outbreaks of the Bubonic Plague in Europe. According to descriptions, the costumes were typically composed of heavy fabric or leather and was waxed.[13][14]

Significance

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California Governor Gavin Newsom speaks about PPE shortages and purchases in May 2020.

Medical textiles have a critical role in preserving human life. So, e.g., medical textile applications (PPE cover all, N95 masks), were in high demand and scarce supply during the COVID-19 pandemic, resulting in severe shortages.[6][15][7] Considering the shortage, in February 2020, the World Health Organization restricted the use of medical essentials such as PPE and masks, etc. to front-line workers only (PPE includes gowns, aprons, masks, gloves, medical masks, goggles, face shields, and respirators, i.e., N95 or FFP2).[16] PPE protects medical professionals from illness, infections [from virus or bacteria]. The PPE cloth acts as a barrier with the capacity to prevent contaminants from entering the body through respiratory secretions, blood, and bodily fluids.[17]

Masks can protect healthy people from illness by limiting the spread of respiratory droplets and aerosols.[18]

Types

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Categories of fibers, fabrics and materials

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There are four different groups of fibers, fabrics and materials used in medical textile products.

Types of fibers, fabrics and materials in different medical textile products[5]
Category Medical textile products
Extracorporeal devices Artificial organs

such as lung, liver, and kidney, etc.[19]

Implantable materials Vascular grafts,

sutures, artificial joints, and ligaments.[5]: 148 

Non-implantable materials Dressing, bandages,

and plaster, etc.

Hygiene and healthcare products Clothing, surgical gowns,

bedding, and wipes, etc.

Different types of fibers and manufacturing systems are utilized for the production of the various medical textile products.[5]

Extracorporeal devices category

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Extracorporeal devices are the artificial organs that remain outside the body while treating a patient. Extracorporeal devices are useful in hemodialysis and cardiac surgery.[19][20]

Fiber or material types Extracorporeal devices
Viscose (hollow type) Artificial liver[21]
Polyurethane Artificial heart[22]
PP Lungs[21]

Implantable materials category

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Implants are medical devices used to replace a missing biological structure, to sustain a damaged biological structure, or to improve an existing biological structure. In contrast to a transplant, which is biomedical tissue that has been transplanted, medical implants are man-made devices such as artificial ligaments and vascular grafts, etc.[5]: 148 [23]

Fiber or material types Manufacturing system employed Implantable materials[5]: 149 
Polyester, Polytetrafluoroethylene Weaving, Knitting Cardiovascular implants such as vascular grafts and heart valves
Silicone, Polyethylene, Polyoxymethylene Orthopedic implants such as artificial bones and joints
Polylactic acid, Polyglycolide, Collagen Monofilament or braided Biodegradable surgical sutures
Steel, Polytetrafluoroethylene, Polyester, Nylon Monofilament or braided Non-biodegradable surgical sutures
Soft tissue implants such as the following:
Polyester, Carbon Braiding Ligaments
Low-density polyethylene Nonwoven Cartilage

Non-implantable materials category

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Non-implantable materials are used externally and may or may not contact skin. For example, bandages, plaster, orthopedic belts, pressure garments, etc.[24][5]: 147, 148 

Fiber or material types Manufacturing system employed Non-implantable materials[21][5]: 141 to 148 
Nylon, Cotton, and Spandex Knitting and Weaving Compression bandages
Cotton, Viscose, Polyamide, and Spandex Weaving, Knitting, and Nonwoven Ordinary bandages which are elastic or non-elastic
Cotton, Viscose, Polyurethane foam, Polypropylene, and Polyester Weaving, Nonwoven Orthopedic bandages
Cotton, Viscose Knitting, Weaving Gauges
Cotton, Viscose, Plastic films, Glass, Polypropylene, and Polyester Knitting, Weaving, and Nonwoven Plasters
Cotton, Viscose Nonwoven Absorbent pads in wound care
Cotton, Chitosan Weaving Antimicrobial dressings[25][26][1]: 145–151 

Hygiene and healthcare products category

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The term "hygiene and healthcare products" refers to a variety of materials used to maintain the hygiene, safety, and care of medical professionals and patients.[5]: 157  Surgical drapes, gowns, uniforms, clothing, caps, wipes, masks, and hospital bed linens are all included in this category[27]

Fiber types Manufacturing system employed Hygiene and healthcare products[27]
Polyester, Polypropylene Nonwoven Protective clothes
Cotton, Polyester Weaving Uniforms
Polyester, Polypropylene, Cotton Weaving, Nonwoven Medical gowns
Polyester, Viscose, Glass Nonwoven Masks
Cotton Weaving Sheets and Pillow covers
Polyester, Cotton Weaving, Knitting Blankets
Polyester, Superabsorbent polymer Nonwoven Diapers[27]

Human textiles

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Human textiles refer to textiles that utilize human materials, including bioengineered yarns made from human cells, for tissue regeneration. Textiles manufactured from human tissue-based 'yarn' can be intricately woven, knitted, or braided and have the potential to contribute to various applications, ranging from simple biocompatible sutures to complex woven tissues for surgical repairs, thereby aiding in the healing process of injuries. Human textiles offer a potential solution to mitigate the drawbacks associated with foreign agents that may induce adverse side effects.[28]

Cell-Assembled extracellular Matrix (CAM)

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The Cell-Assembled Extracellular matrix (CAM) is both biologically sound and resilient, allowing for large-scale production suitable for clinical applications utilizing regular, adult human fibroblasts.[28]

Foreign body reaction

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In the medical field, most permanent synthetic biomaterials are considered foreign by the innate immune system. This can lead to a foreign body reaction when implanted.[28][29]

Properties

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Products made from medical textiles are specially engineered textile-based products used in medical applications. These products are used for prevention, care, and hygiene purposes. A combination of properties are considered while selecting the materials, which largely depends upon the particular use. The materials used in medical textile products must have the following properties: strength, softness, biocompatibility, elasticity, flexibility, nontoxicity, noncarcinogenic, non-allergenic, and air and water permeability.[5]: 136, 137 

Biotextiles are constructions made of textile fibers that are employed in both implantable and non-implant applications. Their performance is assessed according to their biofunctionality, biocompatibility, and biostability. For example, biostability in the presence of body fluids and cells.[30]

Material and technologies

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Fibers

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Overview

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Medical devices are commonly made in whole or part from fibers. A medical device is defined as any device intended for medical purposes. It could be a machine, a reagent for use in the lab, software, an appliance, an instrument, or an implant.[31] For medical use, fiber selection is based on certain criteria of intended use. Primarily, fibers are chosen on the basis of their biodegradability or non-biodegradability. Other than biodegradability, strength, elasticity, and absorbency are also considered.

Natural fibers

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Natural fibers such as cotton, silk, and viscose (a regenerated cellulosic fiber) are used in hygiene and healthcare products, as well as non-implantable materials. Polyester, nylon, polypropylene, glass, and carbon are all examples of synthetic fibers used in Medical textiles.[5]: 136  Fibers absorbed within three months by our biological system are considered biodegradable, and fibers that require more than six months to absorb are called non-biodegradable. These fibers are categorized as below:[5]: 136, 137 

Biodegradable Non-biodegradable
Fibers Cotton Polyester
Viscose Polypropylene
Polyamide Polytetrafluoroethylene
Polyurethane

PLA and PGA fibers

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Sutures made from polyglycolic acid. These sutures are adsorbable and are degraded by the body over time.

Polylactic acid, also called PLA, is a biodegradable, biosorbable or bioabsorbable polymer used in producing many type of implants such as naturally dissolving stents.[5]: 140  Polyglycolide or polyglycolic acid, also called PGA, is a biodegradable and thermoplastic polymer.[32] PGA suture is categorized as an absorbable synthetic braided multifilament.[33]

Other polymers

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Biodegradable Non-biodegradable
Polymers Alginate
Collagen
Chitin
Chitosan

Recent developments

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The term "medical textile" refers to various products made of textile materials (fiber, yarn, or fabric) that are used in the medical environment. Although both natural and synthetic fibers are used in medical textiles, properties such as modulus of elasticity, tensile strength, and hardness are mostly fixed factors in natural fibers, and have proven to be more manageable in synthetic fibers.[10]: 2  Recent fiber developments have a significant impact on four primary areas of medical textiles: hygiene products, implants, non-implantable medical textiles, and extracorporeal medical textiles.[10]

Medical textiles serve as a bridge between biological sciences and engineering.[34]: xxxiii  The advancement of materials science and related research has resulted in the introduction of new fiber materials and manufacturing processes for the medical sector. As a result of new technologies such as 3D printing, electrospinning and melt blowing technology in textiles, medical professions now have access to a diverse choice of textile materials with varying designs and qualities.[2]

Melt blowing is a well-established technology for fabricating micro- and nanofibers, in which a polymer melt is extruded via small nozzles surrounded by a high-speed blowing gas. Melt-blown microfibers typically have a fiber diameter of 2–4 μm, but can be as small as 0.3–0.6 μm or as large as 15–20 μm. Melt blowing technology helps in producing filtering products such as N95 masks, and female hygiene products.[35][36]

Medical textiles use tubular fabrics with carefully chosen materials that are biocompatible, nonallergic, and nontoxic. For example, Dyneema, PTFE, Polyester, and Teflon are used for implants. The material type varies depending on the implant area; for example, Polytetrafluoroethylene is preferred for stent implants due to its non-stick properties, while polyolefin is used for mesh implants.[37][38]

Vectran, a manufactured fiber from liquid-crystal polymer, is used in producing medical devices, for example, implants and certain surgical devices.[39]

Intelligent textiles can be used for disease management as well as remote monitoring.[40]: 373  Intelligent textiles can monitor heart rate and blood pressure, which are critical components of medical diagnosis, and controlling them considerably reduces the incidence of serious health disorders. Movement patterns and electroencephalograms are used to diagnose neurological illnesses and to guide treatment decisions.[40]: 375 

Phase-change materials are helpful in medical textiles because they can be utilized to reheat hypothermia patients softly and precisely. Additionally, the PCM can be incorporated therapeutically into elastic wraps or orthopedic joint supports. It makes it easy to provide heat or cold therapy to joints or muscles while wearing a bandage.[40]: 54, 55 

Materials with shape-memory polymers that have the capabilities of temperature adaptive moisture management can improve the thermo-physiological comfort of patients.[41]

Nonwoven fabrics with two or more fibers layers are widely used in a variety of applications, including tissue engineering scaffolds, wipes, wound dressings, and barrier materials.[42]

Microfluidic spinning technology is used for fabricating many type of fibers. Due to its ease of manipulation, high efficiency, controllability, and environmentally friendly chemical process, microfluidic systems have been identified as an appropriate microreactor platform for the production of anisotropic fibers.[43][44]

Applications

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Medical textiles cover a vast area of application that includes wound care, disease management, preventive clothing, bandages, hygiene (hospital linen), etc. Medical textiles are useful in first aid, treating a wound or keeping a wound or illness in the right condition during medical treatment, they also helps in protecting the healthcare workers from Infection and infectious diseases.[2]

Wound care

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Knitting, weaving, braiding, crocheting, composite materials, and non-woven technologies are all different fabric manufacturing systems used in contemporary wound care.[45] Research subjects in medical textiles include materials and products with significantly superior attributes produced using advanced technology and novel methodologies. New medical textiles are an emerging field with significant growth in wound treatment products. These are all important characteristics of wound care fibers and dressings. They are non-toxic, non-allergic, absorbent, hemostatic, biocompatible, breathable, and non-toxic. They also have good mechanical properties. Chitosan, Alginate, Collagen, branan ferulate, and carbon fiber-based goods offer numerous advantages over conventional materials. Materials used in wound care also include foams, hydrogels, films, hydrocolloids, and matrix (tissue engineering).[45]

Tissue engineering

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Textile technologies are now being considered for biofabrication. The physical and chemical properties of fibers, the size of the pores, and the strength of the fabric all play a role in how textile technologies can be used in tissue engineering.[46] Fibrous structures can be made and shaped with textile technology to meet the needs of a wide range of tissue engineering applications. Tissue engineering is the process of putting together scaffolds, cells, and biologically active molecules to make functional tissues.[47][48]

  • It is possible to make meter-long core-shell hydrogel microfibers that contain ECM proteins and mature cells or somatic stem cells in a microfluidic device. and these microfibers have the morphologies and functions of live tissues. The fibers also have the potential to be reeled and spin or weave[49]
  • Electrospinning can produce nanofibers with a range of desired fine microns that is usable to make nano- and submicron-sized fibrous scaffolds from polymer solutions that could be used as cell and tissue substrates.[50]
Biomedical scaffolds
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Hydrogel fibers are used to construct scaffolds for the development of cells and the release of drugs.[48][51]

Antimicrobial dressing

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Chitosan may function as an inhibitor of bacterial and fungal development.[25] In 2003, the United States Food and Drug Administration approved chitosan-based wound dressings for medical use.[26] Combat medics use Hemcon dressings, which is a dressing with Chitosan, to treat wounds because it stops the blood flow with its hemostasis properties.[25][26] Chitosan hemostatic agents are salts formed when chitosan is combined with an organic acid (lactic acid, or Succinic acid). The hemostatic agent operates by interacting with the erythrocytes' (negatively charged) cell membrane and the protonated chitosan (positively charged), resulting in platelet involvement and fast thrombus formation.[52] When the bandage comes into contact with blood, it becomes sticky, creating an adhesive-like effect that seals the cut.[53]

Surgical suture thread

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Materials in surgical sutures are textile based products. Suture material is frequently subdivided into absorbable thread and non-absorbable thread, and then into synthetic fibers and natural fibers. Whether a suture material is monofilament or polyfilament is an additional critical distinction.[54]

Bandages

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A bandage is a piece of fabric used to cover, dress, and bind wounds. Bandages are typically manufactured from various textile materials. The dressing or splint is held in place using a bandage. Bandages are also used for medical purposes (strengthening and compressing) to support and restrict specific body parts.[55][5]: 142 

Compression bandages

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Compression bandages are used to apply pressure while directed pressure is used to treat lymphatic disease or venous disease,[1]: 111, 241  such as in the treatment of deep vein thrombosis.[5]: 142  The most common classifications for compression bandages are inelastic and elastic.[56]

Antimicrobial textiles

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Antimicrobial textiles are the textile materials (fibers, yarns and fabrics) treated with antimicrobial agents, they are used in hygiene care. Antimicrobial treated textiles either kill the bacteria or inhibit the growth of microorganisms. The exemplary products are wipes, gowns, Odorless clothes, etc.[57] Antimicrobial scrubs are hospital garments treated with anti bacterial chemicals. Their primary objective is to prevent the spread of hazardous microorganisms between healthcare staff and between patients. The applied chemicals work differently, for example, chemical binds to the microbe's DNA, effectively rendering reproduction impossible. Some antimicrobial chemicals dissolve the protein necessary for their growth, there are antimicrobials which attack specific bacteria such as Staphylococcus, Salmonella, and Escherichia coli.[58]

Antiviral textiles

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Antiviral textiles are an extension of antimicrobial surfaces. These surfaces, which have antiviral capabilities, may be able to inactivate lipid-coated viruses.[59] Polyhexamethylene biguanide (PHMB) treated CVC fabric (fabric with chief value cotton) kills 94% of the coronavirus in two hours. Henceforth, it is suitable for PPE for health workers.[60] Chitosan, a natural polymer that is biocompatible, non-allergenic, biodegradable, and non-toxic, was also looked at for its antiviral properties. The chitosan-based compound also shows efficacy against severe acute respiratory syndrome coronavirus 2 and cotton fabrics treated with copper along with chitosan and citric acid. The treated material sustains the antiviral properties five to ten home laundry washes.[61]

Medical gowns

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Surgeons wearing medical gowns

Medical gowns are a kind of PPE for medical professionals. Gowns are a component of a comprehensive infection-control approach. They protect the wearer from getting sick or getting infected if they come into contact with liquids or solids that could be contagious or harmful. Operating room gowns, surgical gowns, isolation gowns, nonsurgical gowns, and procedural gowns are all terms used to describe different gowns used in health care settings. The names of products are not standardized. The specifications of the products are important. ANSI/AAMI PB70 specifies a classification system for protective gear [including isolation gowns and surgical gowns] used in healthcare facilities in the United States based on its liquid barrier performance. Quality requirements for various gowns include seam strength, lint generation, tear resistance, evaporative resistance, and breathability. ASTM International [ASTM F2407] guidelines include a list of them which are approved by FDA.[62]

These gowns are either impermeable or made of a densely woven, water-resistant fabric.[63] 510(K) is a premarket submission made to the Food and Drug Administration in order to demonstrate that the device to be sold is safe and effective. Surgical and surgical isolation gowns are regulated by the FDA as Class II medical devices that require a 510(k). Non-surgical gowns are class I medical devices that do not need a 510(k) clearance.[64]

The different levels are categorized as follows:[62]

Level Risk Exposure Product usable as/at Protection levels Tests
One Minimum Standard isolation, Basic care Visitor gown Allows small amount of fluid penetration. Slight barrier to fluids. Only one test of water impacting the gown material's surface is conducted to determine barrier protection.
Two Low Surgical suturing, and during blood draw Pathology lab, Intensive care unit Protection from fluids for longer period than level one gowns. Two tests
  1. Water impact on gown's surface for barrier protection.
  2. Pressure test of the material.
Three Moderate Intravenous therapy, and to draw arterial blood In Trauma cases, or at Emergency Protection from fluids for longer period than level two gowns. Two tests
  1. Water impact on gown's surface for barrier protection.
  2. Pressure test of the material.
Four High Surgery, and where pathogen transmission suspected Operating theater Protection against fluids and virus for one hour. Three tests
  1. Water impact on gown's surface for barrier protection.
  2. Pressure test of the material.
  3. Barrier protection level against simulated blood containing virus

Some more examples of medical textile applications in the medical environment include the following:

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.

References

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  1. ^ a b c d e f g h Qin, Yimin (2015-11-21). Medical Textile Materials. Woodhead Publishing. pp. 13, 14. ISBN 978-0-08-100624-5.
  2. ^ a b c d e Rohani Shirvan, Anahita; Nouri, Alireza (2020). "Medical textiles". Advances in Functional and Protective Textiles. pp. 291–333. doi:10.1016/B978-0-12-820257-9.00013-8. ISBN 978-0-12-820257-9.
  3. ^ Anand, Subhash C.; Kennedy, J. F.; Miraftab, M.; Rajendran, Subbiyan (2005-11-30). Medical Textiles and Biomaterials for Healthcare. Elsevier. p. 81. ISBN 978-1-84569-410-4.
  4. ^ King, M.W.; Gupta, B.S.; Guidoin, R. (2013). "Introduction". Biotextiles as Medical Implants. pp. xxxi–xxxvii. doi:10.1016/B978-1-84569-439-5.50027-2. ISBN 978-1-84569-439-5.
  5. ^ a b c d e f g h i j k l m n o Horrocks, A. R.; Anand, Subhash C. (2016-03-09). Handbook of Technical Textiles: Technical Textile Applications. Woodhead Publishing. p. 135. ISBN 978-1-78242-488-8.
  6. ^ a b Lopez, German (2020-03-27). "Why America ran out of protective masks — and what can be done about it". Vox. Retrieved 2022-05-01.
  7. ^ a b "Coronavirus: Protective health gear, N-95 masks, coveralls in short supply". Business Today. 23 March 2020. Retrieved 2022-05-01.
  8. ^ "Textile industry focusing on medical garments amid COVID-19 pandemic: TRSA Reports - The Textile Magazine". 21 April 2020. Retrieved 2022-05-04.
  9. ^ "一罩难求:南都民调实测走访发现,线上线下口罩基本卖脱销_进货". www.sohu.com. Retrieved 2022-05-04.
  10. ^ a b c Modified fibers with medical and specialty applications. Dordrecht: Springer. 2006. p. 1. ISBN 978-1-4020-3793-1.
  11. ^ Fess, Elaine Ewing (April 2002). "A History of splinting: To understand the present, view the past". Journal of Hand Therapy. 15 (2): 97–132. doi:10.1053/hanthe.2002.v15.0150091. PMID 12086034.
  12. ^ Susruta; Bhishagratna, Kunja Lal (1907–1916). An English translation of the Sushruta samhita, based on original Sanskrit text. Edited and published by Kaviraj Kunja Lal Bhishagratna. With a full and comprehensive introd., translation of different readings, notes, comparative views, index, glossary and plates. Gerstein - University of Toronto. Calcutta. p. 166.
  13. ^ Encyclopedia of Pestilence Pandemics and Plagues.pdf
  14. ^ Bauer, S. Wise (2003). The Middle Ages: From the Fall of Rome to the Rise of the Renaissance. Peace Hill Press. p. 145. ISBN 978-0-9714129-4-1.
  15. ^ "N95 and rapid testing shortage hits Calgary". calgaryherald. Retrieved 2022-05-01.
  16. ^ Rational use of personal protective equipment for coronavirus disease 2019 (COVID-19) [1]
  17. ^ Health, Center for Devices and Radiological (2020-05-11). "Personal Protective Equipment for Infection Control". FDA. Retrieved 2022-05-02.
  18. ^ Catching, Adam; Capponi, Sara; Yeh, Ming Te; Bianco, Simone; Andino, Raul (6 August 2021). "Examining the interplay between face mask usage, asymptomatic transmission, and social distancing on the spread of COVID-19". Scientific Reports. 11 (1): 15998. Bibcode:2021NatSR..1115998C. doi:10.1038/s41598-021-94960-5. PMC 8346500. PMID 34362936.
  19. ^ a b Churchill Livingstone's mini encyclopaedia of nursing. Edinburgh ; New York: Elsevier/Churchill Livingstone. 2005. p. 200. ISBN 978-0-443-07487-5.
  20. ^ Saravanan, M. (2014-09-01). "Extracorporeal textiles". 61: 88–91. {{cite journal}}: Cite journal requires |journal= (help)[full citation needed]
  21. ^ a b c Ramachandran Sharma, Bhavna; Vaishnav, Rushikesh (April 2015). "Need of Development in Medical Textile Market in India". International Journal on Textile Engineering and Processes. 1 (2): 24–27.
  22. ^ "Artificial Heart | PDF | Polyurethane | Polymers". Scribd. Retrieved 2022-05-16.
  23. ^ Wong, Joyce Y.; Bronzino, Joseph D.; Peterson, Donald R. (2012-12-06). Biomaterials: Principles and Practices. CRC Press. p. 281. ISBN 978-1-4398-7251-2.
  24. ^ "Non implantable materials in medical textiles". International Journal of Current Research.
  25. ^ a b c Ducheyne, Paul; Healy, Kevin E.; Hutmacher, Dietmar W.; Grainger, David W.; Kirkpatrick, C. James (2015-08-28). Comprehensive Biomaterials. Elsevier. pp. 221–235. ISBN 978-0-08-055294-1.
  26. ^ a b c Zhang, Yin-Juan; Gao, Bo; Liu, Xi-Wen (2015). "Topical and effective hemostatic medicines in the battlefield". International Journal of Clinical and Experimental Medicine. 8 (1): 10–19. PMC 4358424. PMID 25784969.
  27. ^ a b c Rajendran, S.; Anand, S.C.; Rigby, A.J. (2016). "Textiles for healthcare and medical applications". Handbook of Technical Textiles. pp. 135–168. doi:10.1016/B978-1-78242-465-9.00005-7. ISBN 978-1-78242-465-9.
  28. ^ a b c Magnan, Laure; Labrunie, Gaëlle; Fénelon, Mathilde; Dusserre, Nathalie; Foulc, Marie-Pierre; Lafourcade, Mickaël; Svahn, Isabelle; Gontier, Etienne; Vélez V., Jaime H.; McAllister, Todd N.; L'Heureux, Nicolas (March 2020). "Human textiles: A cell-synthesized yarn as a truly "bio" material for tissue engineering applications". Acta Biomaterialia. 105: 111–120. doi:10.1016/j.actbio.2020.01.037. PMID 31996332.
  29. ^ Jones, Kim S. (April 2008). "Effects of biomaterial-induced inflammation on fibrosis and rejection". Seminars in Immunology. 20 (2): 130–136. doi:10.1016/j.smim.2007.11.005. PMID 18191409.
  30. ^ Cvrček, Ladislav; Horáková, Marta (2019). "Plasma Modified Polymeric Materials for Implant Applications". Non-Thermal Plasma Technology for Polymeric Materials. pp. 367–407. doi:10.1016/B978-0-12-813152-7.00014-7. ISBN 978-0-12-813152-7.
  31. ^ "Medical devices". www.who.int. Retrieved 2022-05-05.
  32. ^ Gilding, D.K.; Reed, A.M. (December 1979). "Biodegradable polymers for use in surgery—polyglycolic/poly(actic acid) homo- and copolymers: 1". Polymer. 20 (12): 1459–1464. doi:10.1016/0032-3861(79)90009-0.
  33. ^ "Synthetic Biodegradable Polymers as Medical Devices (MPB archive, Mar 98)". 2007-03-12. Archived from the original on 2007-03-12. Retrieved 2022-05-07.
  34. ^ Bartels, V. (2011-08-19). Handbook of Medical Textiles. Elsevier. ISBN 978-0-85709-369-1.
  35. ^ Soltani, Iman; Macosko, Christopher W. (June 2018). "Influence of rheology and surface properties on morphology of nanofibers derived from islands-in-the-sea meltblown nonwovens". Polymer. 145: 21–30. doi:10.1016/j.polymer.2018.04.051. S2CID 139262140.
  36. ^ Wehmann, Michael; McCulloch, W. John G. (1999). "Melt blowing technology". Polypropylene. Polymer Science and Technology Series. Vol. 2. pp. 415–420. doi:10.1007/978-94-011-4421-6_58. ISBN 978-94-010-5899-5.
  37. ^ Gandhi, Kim (2019-11-01). Woven Textiles: Principles, Technologies and Applications. Woodhead Publishing. p. 332. ISBN 978-0-08-102498-0.
  38. ^ Chen, Xiaogang (2015-05-28). Advances in 3D Textiles. Elsevier. p. 324. ISBN 978-1-78242-219-8.
  39. ^ McQuaid, Matilda (2005). Extreme textiles : designing for high performance. New York : Smithsonian Cooper-Hewitt, National Design Museum: Princeton Architectural Press. p. 74. ISBN 978-1-56898-507-7.
  40. ^ a b c Intelligent textiles and clothing. Boca Raton : CRC Press ; Cambridge: Woodhead Pub. 2006. ISBN 978-1-84569-005-2.
  41. ^ Intelligent textiles and clothing. Boca Raton : CRC Press ; Cambridge: Woodhead Pub. 2006. p. 119. ISBN 978-1-84569-005-2.
  42. ^ Kellie, George (2016-05-17). Advances in Technical Nonwovens. Woodhead Publishing. p. 230. ISBN 978-0-08-100584-2.
  43. ^ Xu, Ling-Ling; Wang, Cai-Feng; Chen, Su (7 April 2014). "Microarrays Formed by Microfluidic Spinning as Multidimensional Microreactors". Angewandte Chemie International Edition. 53 (15): 3988–3992. doi:10.1002/anie.201310977. PMID 24595996.
  44. ^ Zhang, Yan; Wang, Cai-Feng; Chen, Li; Chen, Su; Ryan, Anthony J. (December 2015). "Microfluidic-Spinning-Directed Microreactors Toward Generation of Multiple Nanocrystals Loaded Anisotropic Fluorescent Microfibers". Advanced Functional Materials. 25 (47): 7253–7262. doi:10.1002/adfm.201503680. S2CID 136813842.
  45. ^ a b Petrulyte, Salvinija (2008). "Advanced textile materials and biopolymers in wound management". Danish Medical Bulletin. 55 (1): 72–77. PMID 18321446.
  46. ^ Akbari, Mohsen; Tamayol, Ali; Bagherifard, Sara; Serex, Ludovic; Mostafalu, Pooria; Faramarzi, Negar; Mohammadi, Mohammad Hossein; Khademhosseini, Ali (April 2016). "Textile Technologies and Tissue Engineering: A Path Toward Organ Weaving". Advanced Healthcare Materials. 5 (7): 751–766. doi:10.1002/adhm.201500517. PMC 4910159. PMID 26924450.
  47. ^ "Tissue Engineering and Regenerative Medicine". www.nibib.nih.gov. Retrieved 2022-04-26.
  48. ^ a b Du, Xiang-Yun; Li, Qing; Wu, Guan; Chen, Su (December 2019). "Multifunctional Micro/Nanoscale Fibers Based on Microfluidic Spinning Technology". Advanced Materials. 31 (52): e1903733. Bibcode:2019AdM....3103733D. doi:10.1002/adma.201903733. PMID 31573714. S2CID 203622435.
  49. ^ Onoe, Hiroaki; Okitsu, Teru; Itou, Akane; Kato-Negishi, Midori; Gojo, Riho; Kiriya, Daisuke; Sato, Koji; Miura, Shigenori; Iwanaga, Shintaroh; Kuribayashi-Shigetomi, Kaori; Matsunaga, Yukiko T.; Shimoyama, Yuto; Takeuchi, Shoji (June 2013). "Metre-long cell-laden microfibres exhibit tissue morphologies and functions". Nature Materials. 12 (6): 584–590. Bibcode:2013NatMa..12..584O. doi:10.1038/nmat3606. PMID 23542870.
  50. ^ Hu, Jiang; Ma, Peter X. (June 2011). "Nano-Fibrous Tissue Engineering Scaffolds Capable of Growth Factor Delivery". Pharmaceutical Research. 28 (6): 1273–1281. doi:10.1007/s11095-011-0367-z. PMC 3100424. PMID 21234657.
  51. ^ Sharifi, Farrokh; Patel, Bhavika B.; McNamara, Marilyn C.; Meis, Peter J.; Roghair, Marissa N.; Lu, Mingchang; Montazami, Reza; Sakaguchi, Donald S.; Hashemi, Nicole N. (22 May 2019). "Photo-Cross-Linked Poly(ethylene glycol) Diacrylate Hydrogels: Spherical Microparticles to Bow Tie-Shaped Microfibers". ACS Applied Materials & Interfaces. 11 (20): 18797–18807. doi:10.1021/acsami.9b05555. PMID 31042026. S2CID 206497224.
  52. ^ Baldrick, Paul (April 2010). "The safety of chitosan as a pharmaceutical excipient". Regulatory Toxicology and Pharmacology. 56 (3): 290–299. doi:10.1016/j.yrtph.2009.09.015. PMID 19788905.
  53. ^ Singh, Rita; Shitiz, Kirti; Singh, Antaryami (December 2017). "Chitin and chitosan: biopolymers for wound management". International Wound Journal. 14 (6): 1276–1289. doi:10.1111/iwj.12797. PMC 7949833. PMID 28799228.
  54. ^ Sutton, Jeffrey M. (2018). The Mont Reid Surgical Handbook. Elsevier. pp. 81–90. ISBN 978-0-323-53175-7.
  55. ^ "Definition of BANDAGE". www.merriam-webster.com. Retrieved 2022-05-08.
  56. ^ Rajendran, S.; Anand, S.C.; Rajendran, S. (2019). "Advanced textiles for wound compression". Advanced Textiles for Wound Care. pp. 169–192. doi:10.1016/B978-0-08-102192-7.00006-0. ISBN 978-0-08-102192-7.
  57. ^ Sun, Gang (2016-04-11). Antimicrobial Textiles. Woodhead Publishing. ISBN 978-0-08-100585-9.
  58. ^ wpiqadmin (2019-11-14). "How Antimicrobial Scrubs and Uniforms Can Keep Your Workplace Safe?". IQ Apparel. Retrieved 2022-05-02.
  59. ^ Iyigundogdu, Zeynep Ustaoglu; Demir, Okan; Asutay, Ayla Burcin; Sahin, Fikrettin (2017). "Developing Novel Antimicrobial and Antiviral Textile Products". Applied Biochemistry and Biotechnology. 181 (3): 1155–1166. doi:10.1007/s12010-016-2275-5. PMC 7091037. PMID 27734286.
  60. ^ Wang, Wen-Yi; Yim, Sui-Lung; Wong, Chun-Ho; Kan, Chi-Wai (2021). "Development of Antiviral CVC (Chief Value Cotton) Fabric". Polymers. 13 (16): 2601. doi:10.3390/polym13162601. PMC 8400859. PMID 34451140.
  61. ^ Favatela, María Florencia; Otarola, Jessica; Ayala-Peña, Victoria Belen; Dolcini, Guillermina; Perez, Sandra; Torres Nicolini, Andrés; Alvarez, Vera Alejandra; Lassalle, Verónica Leticia (April 2022). "Development and Characterization of Antimicrobial Textiles from Chitosan-Based Compounds: Possible Biomaterials Against SARS-CoV-2 Viruses". Journal of Inorganic and Organometallic Polymers and Materials. 32 (4): 1473–1486. doi:10.1007/s10904-021-02192-x. PMC 8794601. PMID 35106063.
  62. ^ a b Health, Center for Devices and Radiological (2021-01-13). "Medical Gowns". FDA.
  63. ^ Ammirati, Christie T. (2005). "Aseptic Technique". Surgery of the Skin. pp. 25–37. doi:10.1016/B978-0-323-02752-6.50007-9. ISBN 978-0-323-02752-6.
  64. ^ Submission and Review of Sterility Information in Premarket Notification (510(k)) Submissions for Devices Labeled as Sterile [2]
  65. ^ a b Afp (2020-11-18). "Can surgical masks be reused?". The Hindu. Retrieved 2022-04-26.
  66. ^ "See which masks protect better than others". www.usatoday.com. Retrieved 2022-04-27.
  67. ^ Bartels, V. (2011-08-19). Handbook of Medical Textiles. Elsevier. p. 117. ISBN 978-0-85709-369-1.
  68. ^ "Can face masks protect against COVID-19?". Mayo Clinic. Retrieved 2022-04-26.