Isonotholaenic acid

Isonotholaenic acid
Names
	Preferred IUPAC name 4-Hydroxy-2-methoxy-6-[2-(4-methoxyphenyl)ethyl]benzoic acid
Identifiers
CAS Number	150527-29-0 [[1]];
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL68178;
ChemSpider	8193357;
PubChem CID	10017784;
CompTox Dashboard (EPA)	DTXSID601030446 ;
	InChI InChI=1S/C17H18O5/c1-21-14-7-4-11(5-8-14)3-6-12-9-13(18)10-15(22-2)16(12)17(19)20/h4-5,7-10,18H,3,6H2,1-2H3,(H,19,20) Key: GAWSNXBLUNVZCK-UHFFFAOYSA-N; InChI=1/C17H18O5/c1-21-14-7-4-11(5-8-14)3-6-12-9-13(18)10-15(22-2)16(12)17(19)20/h4-5,7-10,18H,3,6H2,1-2H3,(H,19,20) Key: GAWSNXBLUNVZCK-UHFFFAOYAW;
	SMILES c2cc(OC)ccc2CCc1cc(O)cc(OC)c1C(O)=O;
Properties
Chemical formula	C17H18O5
Molar mass	302.326 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Isonotholaenic acid is a dihydrostilbenoid found in the Andean fern Argyrochosma nivea (formerly Notholaena nivea).^[2] This compound shows an anti-chagasic activity.^[3]

References

^ "KNApSAcK Metabolite Information - C00015795". www.knapsackfamily.com.
^ del Olmo, Esther; Armas, Marlon Garcia; Ybarra, Ma Inèss; Lopez, José Luis; Oporto, Patricia; Giménez, Alberto; Deharo, Eric; San Feliciano, Arturo (2003). "The Imidazo[2,1-a]isoindole System. A New Skeletal Basis for Antiplasmodial Compounds". Bioorganic & Medicinal Chemistry Letters. 13 (16): 2769–2772. doi:10.1016/S0960-894X(03)00509-2. PMID 12873511.
^ del Olmo, Esther; Armas, Marlon Garcia; López-Pérez, JL; Ruiz, G; Vargas, F; Giménez, Alberto; Deharo, Eric; San Feliciano, Arturo (2001). "Anti-Trypanosoma activity of some natural stilbenoids and synthetic related heterocyclic compounds". Bioorganic & Medicinal Chemistry Letters. 11 (20): 2755–2757. doi:10.1016/s0960-894x(01)00562-5. PMID 11591517.

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v t e Dihydrostilbenoids and their glycosides
Dihydrostilbenoids	Batatasin-III (3,3′-dihydroxy-5-methoxybibenzyl) Combretastatin and combretastatin B-1 Dihydro-resveratrol Isonotholaenic acid Lunularic acid Lunularin Notholaenic acid Tyrolobibenzyl A, B and C
Oligomeric forms	Bis(bibenzyls): 13,13'-O-Isoproylidenericcardin D Marchantin B and E Neomarchantin A Plagiochin E Riccardin H Macrocyclic bis(benzyls): Marchantin A and C Riccardin B and C Cyclic bibenzyl-dihydrophenanthrene derivative: Cavicularin