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Hypholomine B

From Wikipedia, the free encyclopedia
Hypholomine B
Names
Preferred IUPAC name
2-(3,4-Dihydroxyphenyl)-6-[(1E)-2-(3,4-dihydroxyphenyl)ethen-1-yl]-3-(4-hydroxy-2-oxo-2H-pyran-6-yl)-2,3-dihydro-4H-furo[3,2-c]pyran-4-one
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C26H18O10/c27-14-9-20(35-22(32)10-14)23-24-21(36-25(23)13-3-6-17(29)19(31)8-13)11-15(34-26(24)33)4-1-12-2-5-16(28)18(30)7-12/h1-11,23,25,27-31H/b4-1+/t23-,25+/m0/s1
    Key: CGMQDMKDINCGOB-NJYVMNEESA-N
  • C1=CC(=C(C=C1/C=C/C2=CC3=C(C(C(O3)C4=CC(=C(C=C4)O)O)C5=CC(=CC(=O)O5)O)C(=O)O2)O)O
Properties
C26H18O10
Molar mass 490.420 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Hypholomine B is a neuraminidase inhibitor isolated from the fungus Phellinus linteus.[1]

References

[edit]
  1. ^ Yeom, JH; Lee, IK; Ki, DW; Lee, MS; Seok, SJ; Yun, BS (2012). "Neuraminidase Inhibitors from the Culture Broth of Phellinus linteus". Mycobiology. 40 (2): 142–4. doi:10.5941/MYCO.2012.40.2.142. PMC 3408306. PMID 22870059.