Draft:P'ng LOKE

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{{P'ng LOKE}}

P'ng Loke is an American parasite immunologist. He is the Chief of the Type 2 Immunity Section and a senior investigator at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH) (1). He was elected as a Fellow to the American Academy of Microbiology in 2025 (2).

P’ng Loke Born: 1974; Penang, Malaysia Citizenship:    United States Alma Mater :   Oxford University, UK (BSc)                        University of Edinburgh, Scotland, UK (PhD) Fields :            Immunology, Parasitology Institutions:    National Institute of Allergy and Infectious Diseases, National Institutes of Health.

Early Life and Education

Loke was born and raised in Penang, Malaysia where he attended Chung Ling High School before completing his International Baccalaureate at the United World College of South East Asia (UWCSEA) in Singapore. Through a Chevening Scholarship, he studied biology at St. Anne’s College, University of Oxford receiving his B.A. in 1997. Loke received his Ph.D. in 2001 from the University of Edinburgh through a Wellcome Trust Four-year PhD Program (3).

Research and Career

Loke moved to the United States for his postdoctoral training in Immunology at UC Berkeley (2001-2004) and Parasitology at UCSF (2004-2007). In 2009, he joined the faculty of NYU School of Medicine and moved to the Laboratory of Parasitic Diseases at NIAID in 2020 as Chief of the Type 2 Immunity Section (1). He is also an adjunct Professor at the University of Pennsylvania (4).    

His research focuses on understanding how helminths or parasitic worm infections regulate the immune response through the microbiome (4). He studied an individual who infected himself with Trichuris trichiura to treat his symptoms of ulcerative colitis to try to understand how the worms can improve inflammation (6) (7). His research group has found that parasitic worms can change the bacterial communities in the intestine to be more anti-inflammatory (8,9,10). His work has advanced the understanding of how helminths could be an important part of the hygiene hypothesis (11). Loke's work integrates multiple disciplines, including immunology, microbiology, and genetics, to advance our understanding of host-parasite interactions and their implications for human health.

==References==

{{reflist}}

1.    https://www.niaid.nih.gov/research/png-loke-phd

2.    https://asm.org/Press-Releases/2025/February/65-Fellows-Elected-Into-the-American-Academy-of-Mi

3.    https://irp.nih.gov/system/files/media/file/2022-01/v28i4-NIH-Catalyst_JULY-AUGUST-2020_2.pdf

4.    https://www.med.upenn.edu/nih-igg-partnership/p’ng-loke-phd.html

5.    https://www.niaid.nih.gov/research/png-loke-phd

6.    https://www.science.org/doi/10.1126/scitranslmed.3001500?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

7.    https://www.npr.org/2010/12/02/131753267/eat-your-worms-the-upside-of-parasites

8.    https://www.npr.org/sections/health-shots/2016/04/14/474221947/when-parasites-could-be-the-treatment-instead-of-the-illness

9.    https://www.science.org/doi/10.1126/science.aaf3229?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

10. https://www.nbcnews.com/health/health-news/these-worms-might-prevent-disease-n556241

11. https://nyulangone.org/news/worm-infection-counters-inflammatory-bowel-disease-drastically-changing-gut-microbiome