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CMP-N-acylneuraminate phosphodiesterase

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CMP-N-acylneuraminate phosphodiesterase
Identifiers
EC no.3.1.4.40
CAS no.55326-41-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

The enzyme CMP-N-acylneuraminate phosphodiesterase (EC 3.1.4.40) catalyzes the reaction

CMP-N-acylneuraminate + H2O CMP + N-acylneuraminate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is CMP-N-acylneuraminate N-acylneuraminohydrolase. Other names in common use include CMP-sialate hydrolase, CMP-sialic acid hydrolase, CMP-N-acylneuraminic acid hydrolase, cytidine monophosphosialic hydrolase, cytidine monophosphosialate hydrolase, cytidine monophosphate-N-acetylneuraminic acid hydrolase, and CMP-N-acetylneuraminate hydrolase.

References

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  • Kean EL, Bighouse KJ (1974). "Cytidine 5′-monophosphosialic acid hydrolase. Subcellular location and properties". J. Biol. Chem. 249 (24): 7813–23. PMID 4372219.