User:Kendalse/GAB2
Project Proposal
By: Ashley Tran, Bryan Tan and Seth Kendall
Summary
Discovery
[edit]In this section we will give a basic overview of the history of the gene including its discovery and advances in our understanding of its function.
Importance
[edit]Description of the importance to cellular function of the protein.
Location
[edit]Description of the physical location of the GAB2 gene on the genome and any importance related to this.
Structure
[edit]Description of the structure of the GAB2 protein.
Function
[edit]More detailed description of the function of the protein in the cell.
Interactions
[edit]Descriptions of the various interactions of the GAB2 protein. Including interactions with Grb2, PTPN11, PLCG2, RICS, PIK3R1, CRKL, AKT1 and SHC1.
Association with Alzheimer’s Disease
[edit]Brief overview of the body of knowledge linking GAB2 to Alzheimer's Disease.