User:Isabellawhiting19/Mitochondrial membrane transport protein/Bibliography
Annotated Bibliography
[edit]- "The outer membrane is porous and freely traversed by ions and small, uncharged molecules through pore-forming membrane proteins (porins), such as the voltage-dependent anion channel VDAC"
- Outer and inner membrane, outer freely permeable, inner on lock down
- "The closed vesicular structure of mitochondria is functionally essential for the chemiosmotic mechanism of oxidative phosphorylation (1), that is, a direct link between the electrochemical proton gradient across the inner membrane and the phosphorylation of ADP to ATP (oxidative phosphorylation)."
- mentions ATD and ADP translocase
- homo and heterodimeric transporters
- number of mitochondrial transporters vary by species (35 for yeast, 52 for humans)
- 53 mitochondrial carriers
- Several mitochondrial amino acid transporters have been identified, but some are still missing, **WE DO NOT HAVE EVERYTHING FIGURED OUT**
- The human mitochondrial ADP/ATP carrier AAC1 (SLC25A4) has three associated pathologies, which are quite different in nature:
- Mutations cause carnitine/acylcarnitine carrier deficiency, an autosomal recessive disorder characterized by severe, neonatal onset with cardiomyopathy or a milder phenotype with hypoglycemia, but no cardiomyopathy- FATTY ACID TRANSPORTER (find exact name)
- table of various mutations and what they cause
Bibliography
[edit]This is where you will compile the bibliography for your Wikipedia assignment. Please refer to the following resources for help:
- ^ Kühlbrandt, Werner (2015-10-29). "Structure and function of mitochondrial membrane protein complexes". BMC Biology. 13 (1): 89. doi:10.1186/s12915-015-0201-x. ISSN 1741-7007. PMC 4625866. PMID 26515107.
{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link) - ^ Wohlrab, Hartmut (2009). "Transport proteins (carriers) of mitochondria". IUBMB Life. 61 (1): 40–46. doi:10.1002/iub.139. ISSN 1521-6551.
- ^ Kunji, Edmund R. S.; King, Martin S.; Ruprecht, Jonathan J.; Thangaratnarajah, Chancievan (2020-08-12). "The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology". Physiology. 35 (5): 302–327. doi:10.1152/physiol.00009.2020. ISSN 1548-9213.
- ^ Palmieri, Ferdinando; Scarcia, Pasquale; Monné, Magnus (2020-04-23). "Diseases Caused by Mutations in Mitochondrial Carrier Genes SLC25: A Review". Biomolecules. 10 (4). doi:10.3390/biom10040655. ISSN 2218-273X. PMC 7226361. PMID 32340404.
{{cite journal}}: CS1 maint: unflagged free DOI (link)
https://iubmb.onlinelibrary.wiley.com/doi/full/10.1002/iub.139[1]