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== This is my Sandbox for practicing my edits for the Wikipedia page Gentamicin. This is a work in progress and will be started and stopped at weird sections until ready for publication.

Biosynthesis

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Mechanism

The reaction mechanism of biosynthesis for Gentamicin is analogous to other aminoglycoside antibiotics. Since Gentamicin is derived from the species Micromonospora, the backbone for this antibiotic is the amino cyclitol deoxystreptamine.[1][2][3]


Gene Expression

The genes being expressed for this specific mechanism are largely unknown, but have been narrowed down to two genes where further research is required to identify the correct gene.[1]


References

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[4] [5] [6]

  1. ^ a b Cite error: The named reference Kumar was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference Yu was invoked but never defined (see the help page).
  3. ^ Cite error: The named reference Dewick was invoked but never defined (see the help page).
  4. ^ Kumar, C.; Himabindu, M.; Jetty, Annapurna (January 2008). "Microbial Biosynthesis and Applications of Gentamicin: A Critical Appraisal". Critical Reviews in Biotechnology. 28 (3): 173–212. doi:10.1080/07388550802262197.
  5. ^ Yu, Yi; Zhang, Qi; Deng, Zixin (2017-05-18). "Parallel pathways in the biosynthesis of aminoglycoside antibiotics". F1000Research. 6: 723. doi:https://doi.org/10.12688/f1000research.11104.1. {{cite journal}}: Check |doi= value (help); External link in |doi= (help)
  6. ^ Dewick, Paul M. (2009). Medicinal natural products : a biosynthetic approach (3rd ed.). Chichester, West Sussex, United Kingdom. pp. 738–750. ISBN 978-0-470-74167-2.{{cite book}}: CS1 maint: location missing publisher (link)