Talk:Rhabdomyosarcoma

Medicine: Hematology-oncology / Pathology Mid‑importance

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Though

Though it provides good information, much of the article doesn't refer to rhabdomyosarcoma. Also, it doesn't have information that you would expect from an article this long, such as treatment (if any) and survival rate. A lot of it seems to be general information about cancer - with large portions dedicated to categorizing cancers and diagnosis at the cellular level. It could probably use some more links for some of the uncommon terms, too.

Thank you for your suggestion! When you feel an article needs improvement, please feel free to make whatever changes you feel are needed. Wikipedia is a wiki, so anyone can edit almost any article by simply following the Edit this page link at the top. You don't even need to log in! (Although there are some reasons why you might like to…) The Wikipedia community encourages you to be bold. Don't worry too much about making honest mistakes—they're likely to be found and corrected quickly. If you're not sure how editing works, check out how to edit a page, or use the sandbox to try out your editing skills. New contributors are always welcome. JFW | T@lk 10:03, 10 Jun 2005 (UTC)

Deleted material

I deleted most of this article, which contains a lot of information about cellular differentiation and pathology but had nothing to do with rhabdomyosarcoma. Since somebody may find this information useful (although not for this article), you can retrieve it here. Pretty much this article needs to start over from scratch. —Brim 05:11, 18 November 2005 (UTC)[reply]

add alternate names

I heard an alternate name: something that ended in -oides... it was in a lecture relating to bleeding from the vagina in peds patients. Thanks.

I think it was this: http://en.wiki.x.io/wiki/Sarcoma_botryoides —Preceding unsigned comment added by 75.43.192.141 (talk) 19:22, 14 September 2008 (UTC)[reply]

things seem wrong

Not an expert but some of the descriptions just sound wrong like if the cancer has metastisized the odds of survival are good...my guess is they are not good...it also sounded similarly weird about the deep things being easy to cut out...not sure but its either written weirdly or just wrong —Preceding unsigned comment added by 128.36.159.189 (talk) 06:13, 14 July 2010 (UTC)[reply]

Undue section in lead

Removed Accurate and quick diagnosis is often difficult due to the heterogeneity of RMS tumors and a lack of strong genetic markers of the disease, although recent research by UVA Health researchers discovered "multiple lines of evidence supporting [the gene] AVIL is powerful driver for both major types of rhabdomyosarcoma," according to researcher Hui Li of the University of Virginia School of Medicine's Department of Pathology and UVA Cancer Center.^[1] Malfunctions in AVIL, Li and his team found, play an essential role in the development of the two main subtypes of rhabdomyosarcoma. In a scientific paper outlining the findings, he and his colleagues describe rhabdomyosarcoma as "addicted" to the gene's excess activity. They ultimately label AVIL a "bona fide oncogene" for rhabdomyosarcoma. as it seems to be a bit too specific for the lead section. Jo-Jo Eumerus (talk) 11:59, 30 January 2024 (UTC)[reply]

References

^ Xie, Zhongqiu; Janczyk, Pawel L.; Shi, Xinrui; Wang, Qiong; Singh, Sandeep; Cornelison, Robert; Xu, Jingjing; Mandell, James W.; Barr, Frederic G.; Li, Hui (2022-06-14). "Rhabdomyosarcomas are oncogene addicted to the activation of AVIL". Proceedings of the National Academy of Sciences. 119 (24): e2118048119. Bibcode:2022PNAS..11918048X. doi:10.1073/pnas.2118048119. ISSN 0027-8424. PMC 9214494. PMID 37146302.

[1] Xie, Zhongqiu; Janczyk, Pawel L.; Shi, Xinrui; Wang, Qiong; Singh, Sandeep; Cornelison, Robert; Xu, Jingjing; Mandell, James W.; Barr, Frederic G.; Li, Hui (2022-06-14). "Rhabdomyosarcomas are oncogene addicted to the activation of AVIL". Proceedings of the National Academy of Sciences. 119 (24): e2118048119. Bibcode:2022PNAS..11918048X. doi:10.1073/pnas.2118048119. ISSN 0027-8424. PMC 9214494. PMID 37146302.

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