Talk:Pseudoautosomal region

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Mbp

Excuse me, but what does this abbreviation and "kbp" stand for? It is not mentioned in the article. —Onore Baka Sama^{(speak | stalk)} 14:22, 25 October 2012 (UTC)[reply]

Mbp = mega base pairs

kbp = kilo base pairs

they are unit of DNA length. 142.20.20.33 (talk) 21:27, 7 June 2013 (UTC)[reply]

PAR3

The paragraph on PAR3 is very technical compared to the rest of the article (which is actually very well written) and uses abbreviations like XTR that are not explained anywhere else. I strongly suggest someone to update this part and maybe double check the reference and recent research on this topic. Thank you. — Preceding unsigned comment added by 143.121.239.183 (talk) 10:13, 25 July 2014 (UTC)[reply]

The paragraph is an incomplete copy from an article abstract. It was created on Sept 25th 2013, probably by the author of the abstract himself - who logged in with an IP address and never made any other contributions. I don't consider this a reliable source.

The scientific community does not currently recognize a PAR3 region, please see: http://www.ncbi.nlm.nih.gov/projects/genome/assembly/grc/human/. The paragraph should be removed. — Preceding unsigned comment added by Meisterflexer (talk • contribs) 16:16, 6 November 2014 (UTC)[reply]

Done[1]. I found that a review article said "Recently, it was claimed that humans may even have PAR3, which is located at Xq21.3/Yp11.2 [Veerappa et al., 2013] and corresponds to the known X-transposed region in the Y chromosome [Skaletsky et al., 2003]. However, since the X-transposed region typically does not undergo recombination [Skaletsky et al., 2003] and unequal allelic exchange in this region has been found only in a few cases of pathology and in less than 2% of normal population [Veerappa et al., 2013], it might be premature to consider the region as a true PAR." --Was a bee (talk) 15:00, 10 May 2017 (UTC)[reply]

References to XTR genes added to Y chromosome (Special:Diff/781904984) in order to complement this change. --Artoria 2e5 contrib 22:06, 23 May 2017 (UTC)[reply]

Anthropocentric bias in article

This article has a heavy focus on the human pseudoautosomal regions (PAR1 and PAR2), and does not talk about the general features shared by all pseudoautosomal regions, or the differences that you see between major lineages (e.g. birds and mammals, or monotremes and therians). There is much more data on this topic now in 2024 (several review articles), and it would be appropriate to update this page accordingly. Citronnel (talk) 12:59, 22 October 2024 (UTC)[reply]