Talk:Microsatellite instability

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Genetics task force (assessed as Mid-importance).
	This article is supported by the Molecular and Cell Biology task force (assessed as Mid-importance).

Propose rename of Structure section to Definition

Propose rename of Structure section to Definition - since that it what it seems to be about. - Rod57 (talk) 19:00, 12 July 2016 (UTC)[reply]

Need details of how it is tested

Need details of how it is tested. eg is it detectable in biopsy micrographs ? Are the micro-satellites in the cell nucleus or the cytoplasm ? Does it need a tumour biopsy ? Does it need DNA sequencing ? etc etc - Rod57 (talk) 19:04, 12 July 2016 (UTC)[reply]

MSI-high status could indicate use of immunotherapy

Latest Immunotherapy Research in Treating Colorectal Cancer quotes "But, clearly, the nivolumab data in conjunction with prior data with pembrolizumab in the same population really cements this concept that immune checkpoint therapy with PD-1 in MSI-high colorectal cancer is a fantastically active option." (further testing needed) - Rod57 (talk) 19:10, 12 July 2016 (UTC)[reply]