Talk:D614G mutation

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This is the talk page of a redirect that targets the page:
• Variants of SARS-CoV-2
Because this page is not frequently watched, present and future discussions, edit requests and requested moves should take place at:
• Talk:Variants of SARS-CoV-2

more than just a redirect!

On 2 November 2020‎ this redirect and D614G-redirect was created.

The term "D614G mutation" seems to be misleading. A mutation is the sum of changes that happen between one variant of the virus and another. Mutations that cause mayor changes in the properties of the virus are leading to another strain, like the changes between SARS-CoV-1 AKA SARS and SARS-CoV-2 AKA New Coronavirus 2019. The subsets of mutations are called changes, whereas D614G is a substitution (changing base {pair} D into G at position 614 of the SARS-CoV-2 genome). Another common change is a deletion Deletion Variant written as <number>del.

Of course the changes between two known variants could have happened during several mutations. But we can not know this, until samples of the intermediate variant(s) is/are detected, isolated, sequenced and published.

I suggest an article D614G Substitution being written on this subject which is creating so much noise in the media and academia. Spike mutation D614G alters SARS-CoV-2 fitness --Manorainjan 15:40, 24 December 2020 (UTC)[reply]

It would need to be D614G substitution (lowercase) ; this should be discussed at talk:Variants of SARS-CoV-2 -- 70.31.205.108 (talk) 14:27, 18 January 2021 (UTC)[reply]