TBC1D9

TBC1D9
Identifiers
Aliases	TBC1D9, MDR1, GRAMD9, TBC1 domain family member 9
External IDs	OMIM: 618035; MGI: 1918560; HomoloGene: 57079; GeneCards: TBC1D9; OMA:TBC1D9 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	140,756,385 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	83,999,563 bp
RNA expression pattern
	Top expressed in
	lactiferous duct; ; Epithelium of choroid plexus; ; palpebral conjunctiva; ; lateral nuclear group of thalamus; ; seminal vesicula; ; visceral pleura; ; spinal ganglia; ; parietal pleura; ; pons; ; trigeminal ganglion;
	Top expressed in
	Epithelium of choroid plexus; ; trigeminal ganglion; ; superior cervical ganglion; ; cerebellar cortex; ; ventral tegmental area; ; lobe of cerebellum; ; visual cortex; ; transitional epithelium of urinary bladder; ; primary visual cortex; ; pontine nuclei;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; calcium ion binding; GTPase activator activity;
Cellular component	endomembrane system; intracellular anatomical structure;
Biological process	activation of GTPase activity; regulation of vesicle fusion; intracellular protein transport;
	Sources:Amigo / QuickGO
Orthologs
	23158
	71310
	ENSG00000109436
	ENSMUSG00000031709
	Q6ZT07
	Q3UYK3
	NM_015130
	NM_001111304; NM_027758
	NP_055945
	NP_001104774; NP_082034
	Wikidata
View/Edit Human	View/Edit Mouse

TBC1 domain family member 9 is a protein that in humans is encoded by the TBC1D9 gene.^[5]^[6]

It is also known as MDR1, GRAMD9.

It is predicted to enable GTPase activator activity. It is also predicted to be involved in activation of GTPase activity and intracellular protein transport.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000109436 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031709 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Islam TC, Asplund AC, Lindvall JM, Nygren L, Liden J, Kimby E, Christensson B, Smith CI, Sander B (Sep 2003). "High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma". Leukemia. 17 (9): 1880–1890. doi:10.1038/sj.leu.2403057. PMID 12970790.
^ "Entrez Gene: TBC1D9 TBC1 domain family, member 9 (with GRAM domain)".
^ "TBC1D9 TBC1 domain family member 9 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2023-11-28.

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–113. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–364. doi:10.1093/dnares/5.6.355. PMID 10048485.
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–3496. Bibcode:2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–716. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–12135. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Rodríguez Nóvoa S, Barreiro P, Rendón A, et al. (2006). "Plasma levels of atazanavir and the risk of hyperbilirubinemia are predicted by the 3435C-->T polymorphism at the multidrug resistance gene 1". Clin. Infect. Dis. 42 (2): 291–295. doi:10.1086/499056. PMID 16355344.

This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000109436 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031709 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12970790-5] Islam TC, Asplund AC, Lindvall JM, Nygren L, Liden J, Kimby E, Christensson B, Smith CI, Sander B (Sep 2003). "High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma". Leukemia. 17 (9): 1880–1890. doi:10.1038/sj.leu.2403057. PMID 12970790.

[entrez-6] "Entrez Gene: TBC1D9 TBC1 domain family, member 9 (with GRAM domain)".

[7] "TBC1D9 TBC1 domain family member 9 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2023-11-28.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

References

Further reading