RAI14

RAI14
Identifiers
Aliases	RAI14, NORPEG, RAI13, retinoic acid induced 14
External IDs	OMIM: 606586; MGI: 1922896; HomoloGene: 9199; GeneCards: RAI14; OMA:RAI14 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	34,832,612 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	10,714,710 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; visceral pleura; ; ventricular zone; ; smooth muscle tissue; ; placenta; ; decidua; ; glomerulus; ; amniotic fluid; ; metanephric glomerulus; ; myometrium;
	Top expressed in
	renal corpuscle; ; lumbar spinal ganglion; ; ciliary body; ; left lung lobe; ; iris; ; hair follicle; ; endothelial cell of lymphatic vessel; ; ureter; ; maxillary prominence; ; sciatic nerve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cell cortex; cytoskeleton; nucleus; fibrillar center; cytoplasm; cytosol; cell junction;
Biological process	spermatogenesis; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	26064
	75646
	ENSG00000039560
	ENSMUSG00000022246
	Q9P0K7
	Q9EP71
NM_001145520; NM_001145521; NM_001145522; NM_001145523; NM_001145525;
	NM_015577
	NM_001166408; NM_030690; NM_001356534
NP_001138992; NP_001138993; NP_001138994; NP_001138995; NP_001138997;
	NP_056392
	NP_001159880; NP_109615; NP_001343463
	Wikidata
View/Edit Human	View/Edit Mouse

Ankycorbin is a protein that in humans is encoded by the RAI14 gene.^[5]^[6] Ankycorbin has been associated with the cortical actin cytoskeleton structures in terminal web, cell-cell adhesion sites as well as stress fibres.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000039560 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022246 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kutty RK, Kutty G, Samuel W, Duncan T, Bridges CC, El-Sherbeeny A, Nagineni CN, Smith SB, Wiggert B (May 2001). "Molecular characterization and developmental expression of NORPEG, a novel gene induced by retinoic acid". J Biol Chem. 276 (4): 2831–40. doi:10.1074/jbc.M007421200. PMID 11042181.
^ "Entrez Gene: RAI14 retinoic acid induced 14".
^ Peng YF, Mandai K, Sakisaka T, Okabe N, Yamamoto Y, Yokoyama S, Mizoguchi A, Shiozaki H, Monden M, Takai Y (December 2000). "Ankycorbin: a novel actin cytoskeleton-associated protein". Genes Cells. 5 (12): 1001–8. doi:10.1046/j.1365-2443.2000.00381.x. PMID 11168586. S2CID 19149724.

Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD, Pawson T (August 2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. Bibcode:2004CBio...14.1436J. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325.
Yuan W, Zheng Y, Huo R, Lu L, Huang XY, Yin LL, Li JM, Zhou ZM, Sha JH (September 2005). "Expression of a novel alternative transcript of the novel retinal pigment epithelial cell gene NORPEG in human testes". Asian J. Androl. 7 (3): 277–88. doi:10.1111/j.1745-7262.2005.00040.x. PMID 16110356.
Kutty RK, Chen S, Samuel W, Vijayasarathy C, Duncan T, Tsai JY, Fariss RN, Carper D, Jaworski C, Wiggert B (July 2006). "Cell density-dependent nuclear/cytoplasmic localization of NORPEG (RAI14) protein". Biochem. Biophys. Res. Commun. 345 (4): 1333–41. doi:10.1016/j.bbrc.2006.04.184. PMID 16729964.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000039560 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022246 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11042181-5] Kutty RK, Kutty G, Samuel W, Duncan T, Bridges CC, El-Sherbeeny A, Nagineni CN, Smith SB, Wiggert B (May 2001). "Molecular characterization and developmental expression of NORPEG, a novel gene induced by retinoic acid". J Biol Chem. 276 (4): 2831–40. doi:10.1074/jbc.M007421200. PMID 11042181.

[entrez-6] "Entrez Gene: RAI14 retinoic acid induced 14".

[pmid11168586-7] Peng YF, Mandai K, Sakisaka T, Okabe N, Yamamoto Y, Yokoyama S, Mizoguchi A, Shiozaki H, Monden M, Takai Y (December 2000). "Ankycorbin: a novel actin cytoskeleton-associated protein". Genes Cells. 5 (12): 1001–8. doi:10.1046/j.1365-2443.2000.00381.x. PMID 11168586. S2CID 19149724.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

References

Further reading