Monoethanolamine oleate

Ethanolamine Oleate
Clinical data
AHFS/Drugs.com	Multum Consumer Information
ATC code	C05BB01 (WHO) ;
Identifiers
	IUPAC name 2-Hydroxyethylammonium oleate;
CAS Number	2272-11-9 ;
PubChem CID	5282489;
DrugBank	DB06689 ;
ChemSpider	4445632 ;
UNII	U4RY8MRX7C;
KEGG	D02276 ;
CompTox Dashboard (EPA)	DTXSID8023008 ;
ECHA InfoCard	100.017.163
Chemical and physical data
Formula	C20H41NO3
Molar mass	343.552 g·mol−1
Density	0.974 g/cm3
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Monoethanolamine oleate (ethanolammonium oleate) is an organic compound with the formula [CH₃(CH₂)₇CH=CH(CH₂)₇CO₂][H₃NCH₂CH₂OH].. A colorless oily liquid, it is an example of a protic ionic liquid.^[1] It is a salt formed by the reaction between monoethanolamine and oleic acid.^[2]

Antivaricose agent

As an antivaricose agent, it is injected topically into varicosities to cause sclerosis (closure) of the abnormal vein. It is indicated for the treatment of patients with esophageal varices that have recently bled, to prevent rebleeding. Ethanolamine is not indicated for the treatment of patients with esophageal varices that have not bled. There is no evidence that treatment of this population decreases the likelihood of bleeding. Sclerotherapy with ethanolamine has no beneficial effect upon portal hypertension, the cause of esophageal varices, so that recanalization and collateralization may occur, necessitating reinjection.^[3]

References

^ Toledo Hijo AA, Maximo GJ, Costa MC, Cunha RL, Pereira JF, Kurnia KA, et al. (April 2017). "Phase Behavior and Physical Properties of New Biobased Ionic Liquid Crystals". The Journal of Physical Chemistry B. 121 (14): 3177–3189. doi:10.1021/acs.jpcb.7b01384. PMID 28332847.
^ Álvarez VH, Mattedi S, Martin-Pastor M, Aznar M, Iglesias M (2010). "Synthesis and Thermophysical Properties of Two New Protic Long-Chain Ionic Liquids with the Oleate Anion". Fluid Phase Equilibria. 299: 42–50. doi:10.1016/j.fluid.2010.08.022.
^ "Ethanolamine Oleate". RXList. Retrieved 7 March 2020.

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[1] Toledo Hijo AA, Maximo GJ, Costa MC, Cunha RL, Pereira JF, Kurnia KA, et al. (April 2017). "Phase Behavior and Physical Properties of New Biobased Ionic Liquid Crystals". The Journal of Physical Chemistry B. 121 (14): 3177–3189. doi:10.1021/acs.jpcb.7b01384. PMID 28332847.

[2] Álvarez VH, Mattedi S, Martin-Pastor M, Aznar M, Iglesias M (2010). "Synthesis and Thermophysical Properties of Two New Protic Long-Chain Ionic Liquids with the Oleate Anion". Fluid Phase Equilibria. 299: 42–50. doi:10.1016/j.fluid.2010.08.022.

[3] "Ethanolamine Oleate". RXList. Retrieved 7 March 2020.

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