SERPINB7
(Redirected from Megsin)
Serpin B7 is a protein that in humans is encoded by the SERPINB7 gene.[5]
See also
[edit]References
[edit]- ^ a b c GRCh38: Ensembl release 89: ENSG00000166396 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067001 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7".
Further reading
[edit]- Tsujimoto M, Tsuruoka N, Ishida N, et al. (1997). "Purification, cDNA cloning, and characterization of a new serpin with megakaryocyte maturation activity". J. Biol. Chem. 272 (24): 15373–80. doi:10.1074/jbc.272.24.15373. PMID 9182567.
- Miyata T, Nangaku M, Suzuki D, et al. (1998). "A mesangium-predominant gene, megsin, is a new serpin upregulated in IgA nephropathy". J. Clin. Invest. 102 (4): 828–36. doi:10.1172/JCI2450. PMC 508946. PMID 9710452.
- Inagi R, Miyata T, Suzuki D, et al. (2001). "Specific tissue distribution of megsin, a novel serpin, in the glomerulus and its up-regulation in IgA nephropathy". Biochem. Biophys. Res. Commun. 286 (5): 1098–106. doi:10.1006/bbrc.2001.5509. PMID 11527413.
- Inagi R, Miyata T, Imasawa T, et al. (2003). "Mesangial cell-predominant gene, megsin". Nephrol. Dial. Transplant. 17 Suppl 9 (90009): 32–3. doi:10.1093/ndt/17.suppl_9.32. PMID 12386281.
- Inagi R, Miyata T, Nangaku M, et al. (2003). "Transcriptional regulation of a mesangium-predominant gene, megsin" (PDF). J. Am. Soc. Nephrol. 13 (11): 2715–22. doi:10.1097/01.ASN.0000033507.32175.FA. PMID 12397041.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Li YJ, Du Y, Li CX, et al. (2004). "Family-based association study showing that immunoglobulin A nephropathy is associated with the polymorphisms 2093C and 2180T in the 3' untranslated region of the Megsin gene". J. Am. Soc. Nephrol. 15 (7): 1739–43. doi:10.1097/01.ASN.0000130858.00688.46. PMID 15213261.
- Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Inagi R, Nangaku M, Usuda N, et al. (2005). "Novel serpinopathy in rat kidney and pancreas induced by overexpression of megsin". J. Am. Soc. Nephrol. 16 (5): 1339–49. doi:10.1681/ASN.2004070600. PMID 15788472.
- Xia Y, Li Y, Du Y, et al. (2006). "Association of MEGSIN 2093C-2180T haplotype at the 3' untranslated region with disease severity and progression of IgA nephropathy". Nephrol. Dial. Transplant. 21 (6): 1570–4. doi:10.1093/ndt/gfk096. PMID 16431886.
- Xia YF, Huang S, Li X, et al. (2006). "A family-based association study of megsin A23167G polymorphism with susceptibility and progression of IgA nephropathy in a Chinese population". Clin. Nephrol. 65 (3): 153–9. doi:10.5414/cnp65153. PMID 16550745.
External links
[edit]- The MEROPS online database for peptidases and their inhibitors: I04.012
- SERPINB7+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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