Limulus clotting factor B
| Limulus clotting factor B | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.21.85 | ||||||||
| CAS no. | 848851-53-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Limulus clotting factor B (EC 3.4.21.85) is an enzyme.[1] This enzyme catalyses the following chemical reaction
- Selective cleavage of -Arg98-Ile- bond in limulus proclotting enzyme to form active clotting enzyme
From the hemocyte granules of the horseshoe crabs Limulus and Tachypleus. This enzyme is downstream of Limulus clotting factor C, but upstream of Limulus clotting enzyme.[2]
References
[edit]- ^ Nakamura T, Horiuchi T, Morita T, Iwanaga S (March 1986). "Purification and properties of intracellular clotting factor, factor B, from horseshoe crab (Tachypleus tridentatus) hemocytes". Journal of Biochemistry. 99 (3): 847–57. doi:10.1093/oxfordjournals.jbchem.a135545. PMID 3519594.
- ^ Iwanaga, S (May 2007). "Biochemical principle of Limulus test for detecting bacterial endotoxins". Proceedings of the Japan Academy. Series B, Physical and Biological Sciences. 83 (4): 110–9. Bibcode:2007PJAB...83..110I. doi:10.2183/pjab.83.110. PMC 3756735. PMID 24019589.
External links
[edit]- Limulus+clotting+factor+_overbar_B_ at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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