James Corson Niederman
James Corson Niederman | |
|---|---|
| Born | November 27, 1924 Hamilton, Ohio, U.S. |
| Died | March 2, 2024 (aged 99) Bethany, Connecticut, U.S. |
| Alma mater | Kenyon College, Johns Hopkins School of Medicine |
| Known for | Epstein–Barr virus, infectious mononucleosis |
| Spouse | Mimi (Miriam) Camp Niederman |
| Scientific career | |
| Fields | Virology, epidemiology |
| Institutions | Yale School of Medicine, Yale School of Public Health |
James Corson Niederman (November 27, 1924 – March 2, 2024) was an American epidemiologist whose research identified the Epstein–Barr virus as the cause of infectious mononucleosis in a study published in 1968.[1][2]
Early life and education
[edit]James Corson Niederman was born on November 27, 1924, in Hamilton, Ohio. He graduated from Kenyon College in 1946,[3] and received his medical degree from the Johns Hopkins School of Medicine in 1949. For many years he was a residential college associate at the Yale School of Public Health.[4]
Medical research
[edit]Beginning in the late 1950s, Dr. Niederman and Robert W. McCollum collected sera from Yale University freshmen.[5] Students who tested positive for EBV antibodies never developed infectious mononucleosis (IM). The pre-illness samples of students, who later developed infectious mononucleosis tested negative for EBV antibodies. Therefore, the presence of EBV antibodies indicated immunity from infectious mononucleosis.[6] The study demonstrated that EBV is not simply a passenger virus, it is the etiologic agent of infectious mononucleosis. This was a remarkable discovery, since at the time the cause of IM was a mystery.
Death
[edit]Niederman died at his home in Bethany, Connecticut, on March 2, 2024, at the age of 99.[7]
See also
[edit]References
[edit]- ^ Niederman, James C. (1968). "Infectious Mononucleosis: Clinical Manifestations in Relation to EB Virus Antibodies". JAMA. 203 (3): 205–9. doi:10.1001/jama.1968.03140030037009. PMID 4864269.[permanent dead link]
- ^ Paul, John (1968). "A New Lead in Infectious Mononucleosis". JAMA. 203 (3): 219–20. doi:10.1001/jama.1968.03140030051012. PMID 5694046.
- ^ "Board of Trustees". Kenyon.edu. Retrieved 24 November 2014.
- ^ "James Corson Niederman, MD > Yale School of Public Health - Yale School of Public Health". Publichealth.yale.edu. Archived from the original on 29 November 2014. Retrieved 24 November 2014.
- ^ "This Week's Citation Classic" (PDF). Garfield.library.upenn.edu. Retrieved 24 November 2014.
- ^ "Facts (for a change) on mononucleosis". Kiplinger's Personal Finance. 24: 31. April 1970.
- ^ "James C. Niederman M.D." Legacy. Retrieved 10 March 2024.