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Isofuran

From Wikipedia, the free encyclopedia

Isofurans are nonclassic eicosanoids formed nonenzymatically by free radical mediated peroxidation of arachidonic acid. The isofurans are similar to the isoprostanes and are formed under similar conditions, but contain a substituted tetrahydrofuran ring. The concentration of oxygen affects this process; at elevated oxygen concentrations, the formation of isofurans is favored whereas the formation of isoprostanes is disfavored.[1][2]

References

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  1. ^ Roberts, L. Jackson; Fessel, Joshua P.; Davies, Sean S. (2006-04-05). "The Biochemistry of the Isoprostane, Neuroprostane, and Isofuran Pathways of Lipid Peroxidation". Brain Pathology. 15 (2): 143–148. doi:10.1111/j.1750-3639.2005.tb00511.x. ISSN 1015-6305. PMC 8095955. PMID 15912887.
  2. ^ Roberts, LJ 2nd and Fessel, JP (Mar 2004). "The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation". Chem Phys Lipids. 128 (1–2): 173–86. doi:10.1016/j.chemphyslip.2003.09.016. PMID 15037162.{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: numeric names: authors list (link)