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gut-2 RNA motif

From Wikipedia, the free encyclopedia
gut-2
Consensus secondary structure and sequence conservation of gut-2 RNA
Identifiers
Symbolgut-2
RfamRF02990
Other data
RNA typeGene; sRNA
SOSO:0001263
PDB structuresPDBe


The gut-2 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] gut-2 motif RNAs are found in metagenomic sequences that are derived from animal guts.

It is ambiguous whether gut-2 RNAs function as cis-regulatory elements or whether they operate in trans. Although gut-2 RNAs are often found upstream of protein-coding genes, this does not occur often enough that they were declared as being likely to be cis-regulatory.

References

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  1. ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.