Clostridium-PBP RNA motif
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Clostridium-PBP | |
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![]() Consensus secondary structure and sequence conservation of Clostridium-PBP RNA | |
Identifiers | |
Symbol | Clostridium-PBP |
Rfam | RF03091 |
Other data | |
RNA type | Gene; sRNA |
SO | SO:0001263 |
PDB structures | PDBe |
The Clostridium-PBP RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] Clostridium-PBP motifs are found in organisms in the genus Clostridium.
Structurally, the motif is a hairpin. However, because the sequences determined to match the motif are very closely related, there is limited opportunity to observe covariation, and therefore the predicted structure might be incomplete.
The RNAs are located nearby to the start codons of genes predicted to encode a PBP transporter. The RNAs might therefore regulate these genes as cis-regulatory elements, but it is also possible that they operate in trans.
References
[edit]- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.