CALN1

CALN1
Identifiers
Aliases	CALN1, CABP8, calneuron 1
External IDs	OMIM: 607176; MGI: 2155987; HomoloGene: 10966; GeneCards: CALN1; OMA:CALN1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	72,447,151 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	130,876,253 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; pons; ; pars reticulata; ; cerebellar hemisphere; ; pars compacta; ; right hemisphere of cerebellum; ; entorhinal cortex; ; external globus pallidus; ; Brodmann area 46; ; middle temporal gyrus;
	Top expressed in
	nucleus accumbens; ; dorsal striatum; ; olfactory tubercle; ; facial motor nucleus; ; deep cerebellar nuclei; ; cerebellar cortex; ; globus pallidus; ; cerebellar vermis; ; lobe of cerebellum; ; temporal lobe;
	More reference expression data
	n/a
Orthologs
	83698
	140904
	ENSG00000183166
	ENSMUSG00000060371
	Q9BXU9
	Q9JJG7
	NM_001017440; NM_031468; NM_001363460
	NM_021371; NM_181045
	NP_001017440; NP_113656; NP_001350389
	NP_067346; NP_851388
	Wikidata
View/Edit Human	View/Edit Mouse

Calcium-binding protein 8 is a protein that in humans is encoded by the CALN1 gene.^[5]^[6] Alternative splicing results in multiple transcript variants.^[6]

Function

This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183166 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000060371 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wu YQ, Lin X, Liu CM, Jamrich M, Shaffer LG (Apr 2001). "Identification of a human brain-specific gene, calneuron 1, a new member of the calmodulin superfamily". Molecular Genetics and Metabolism. 72 (4): 343–50. doi:10.1006/mgme.2001.3160. PMID 11286509.
^ ^a ^b "Entrez Gene: CALN1 calneuron 1".
^ McCue HV, Haynes LP, Burgoyne RD (Aug 2010). "The diversity of calcium sensor proteins in the regulation of neuronal function". Cold Spring Harbor Perspectives in Biology. 2 (8): a004085. doi:10.1101/cshperspect.a004085. PMC 2908765. PMID 20668007.

External links

Human CALN1 genome location and CALN1 gene details page in the UCSC Genome Browser.

Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Sanger Centre, The; Washington University Genome Sequencing Cente, The (Nov 1998). "Toward a complete human genome sequence". Genome Research. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.

This article on a gene on human chromosome 7 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000183166 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000060371 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11286509-5] Wu YQ, Lin X, Liu CM, Jamrich M, Shaffer LG (Apr 2001). "Identification of a human brain-specific gene, calneuron 1, a new member of the calmodulin superfamily". Molecular Genetics and Metabolism. 72 (4): 343–50. doi:10.1006/mgme.2001.3160. PMID 11286509.

[entrez-6] "Entrez Gene: CALN1 calneuron 1".

[pmid_20668007-7] McCue HV, Haynes LP, Burgoyne RD (Aug 2010). "The diversity of calcium sensor proteins in the regulation of neuronal function". Cold Spring Harbor Perspectives in Biology. 2 (8): a004085. doi:10.1101/cshperspect.a004085. PMC 2908765. PMID 20668007.

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Function

References

External links

Further reading