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Brandon Colby

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Brandon Ross Colby is an American medical geneticist in Beverly Hills, California[1] and physician specializing in predictive medicine and genetic testing. He is author of Outsmart Your Genes, a book about genetics published in 2011, and he is the founder and CEO of direct-to-consumer genetic testing service Sequencing.[2]

Early life and education

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Colby was born with epidermolysis bullosa simplex (EB), a rare genetic disease that causes heat-sensitivity of the skin, leading to blisters on the hands and feet when skin temperature rises. Because of his condition he had an interest in genetics early in life.

Colby holds a degree in genetics from the University of Michigan, a 2004 Medical Doctorate from Mount Sinai School of Medicine,[1] and a 2007 Master of Business Administration from Stanford University's Graduate School of Business.[3][4]

Career

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Colby founded Existence Genetics in 2005 during his second year at Stanford.[3] The business declared bankruptcy on November 21, 2012. Existence Genetics was a genetic analysis and genetic reporting company that provided the healthcare industry and health & wellness organizations with information about their clients' genes.[5]

Colby was also medical director of Existence Health, a medical practice founded in 2010 and based in Los Angeles that provided predictive medicine services to its patients based upon a person's genes.

Sequencing

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Colby founded Sequencing (sequencing.com), which launched in September 2016. It hosts genomic sequencing data for individuals and for researchers, an API through which third parties can interface with the data, and an app store. The app store allows purchase of further genetic data interpretation, such as results for Alzheimer's disease.[6] Genomics Personalized Health provides genomic sequencing, EncrypGen provides secure data transfer with blockchain, and Sequencing hosts genomic data and offers interpretation of results.[7][8][9] A patent assigned to sequencing.com was filed in 2014.[10][11]

In 2022, Sequencing raised five million dollars in a round of venture capital financing.[12][13] Sequencing has been profiled as a "key company" in ResearchandMarkets.com's whole genome and exome market research reports since 2021.[14][15]

Publications

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Colby co-authored "Congenital erythropoietic porphyria: identification and expression of eight novel mutations in the uroporphyrinogen III synthase gene", which appeared in British Journal of Haematology in 2002. In 2010, Penguin Random House published Colby's Outsmart Your Genes (ISBN 9780399536380), a book about genetic testing and predictive medicine.[16][17][18]

Media appearances

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In April 2011, Colby appeared on the "How to Outsmart Your Genes" episode of the TV show The Doctors. Existence Genetics performed genetic testing on several of the show's guests and Colby discussed the results. The testing focused on male pattern baldness, sexual compatibility, preconception, and disease predisposition.[19]

Colby has also appeared on ABC's Good Morning America in April, 2010, and the Today Show with Megyn Kelly in 2018.[20]

See also

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References

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  1. ^ a b "Licensing details for: A 92750". California Department of Consumer Affairs. Retrieved July 16, 2024.
  2. ^ Rabbitt, Meghan (February 24, 2021). "Tips to Outsmart Genetic Health Risks". Prevention. Retrieved July 17, 2024.
  3. ^ a b Mauriello, Dana (November 2, 2017). "Brandon Colby, MBA '07: Charting the Course for a Predictive Medicine Venture". Stanford Graduate School of Business. Retrieved July 17, 2024.
  4. ^ "Outsmart Your Genes | Dr. Brandon Colby MD". Sequencing.com. Retrieved 2023-02-26.
  5. ^ Steve Parker (8 October 2010). "Existence Genetics Ramps up for Widespread Test Service Launch, Eyes Whole-Genome Sequencing". GenomeWeb. Retrieved 2011-06-01.
  6. ^ Richards, Sarah Elizabeth (February 5, 2018). "Now You Can Genetically Test Your Child For Disease Risks. Should You?". Smithsonian Magazine. Retrieved July 17, 2024.
  7. ^ "EncrypGen, Inc. Add New Alliances: Sequencing.com & Genomics Personalized Health". Marketers Media (Press release). January 29, 2018. Retrieved July 18, 2024.
  8. ^ DNA Can Guide the Way: Genome Mapping Offers Look Into Medical Future. Corpus Christi Caller - Times, July 07, 2016. https://www.proquest.com/newspapers/dna-can-guide-way/docview/2581329790/se-2 (accessed July 19, 2024).
  9. ^ "Sequencing.com launches genetic data platform". ProQuest. ProQuest 1847407330. Retrieved 2024-07-19.
  10. ^ "Researchers Submit Patent Application, "System and Method for Real-Time Personalization Utilizing an Individual'S Genomic Data", for Approval (USPTO 20160321395)". Gale Academic OneFile. NewsRX. November 26, 2016. Retrieved July 18, 2024.
  11. ^ Guerrini, Christi J.; Lewellyn, Meaganne; Majumder, Mary A.; Trejo, Meredith; Canfield, Isabel; McGuire, Amy L. (2019). "Donors, authors, and owners: how is genomic citizen science addressing interests in research outputs?". BMC Medical Ethics. 20 (1): 84. doi:10.1186/s12910-019-0419-1. ISSN 1472-6939. PMC 6868686. PMID 31752834.
  12. ^ "Sequencing.com Raises $5M In Venture Capital". VC News Daily. Massinvestor. November 9, 2022. Retrieved July 18, 2024.
  13. ^ "VC Health Pulse: Expected Gridlock in Washington Shifts Healthcare VCs' Attention to States; Biotech Startup Juvena Therapeutics Grabs $41 Million." Dow Jones Institutional News, November 10, 2022, https://www.proquest.com/wire-feeds/vc-health-pulse-expected-gridlock-washington/docview/2734893339/se-2 (accessed July 19, 2024).
  14. ^ "Whole Genome and Exome Sequencing Market Analysis 2023-2024 and 2027 with Executive and Consultant Guides Featuring llumina, ION, Pacific Biosystems, Roche, SOLiD, Oxford Nanopore Among Others". PR Newswire (Press release). March 28, 2024. Retrieved July 18, 2024.
  15. ^ "Whole Genome And Exome Sequencing Markets, Q4 2021 Market Report - ResearchAndMarkets.com". Business Wire (Press release). October 5, 2021. Retrieved July 18, 2024.
  16. ^ Shady, Amr A.; Colby, Brandon R.; Cunha, Luis F.; Astrin, Kenneth H.; Bishop, David F.; Desnick, Robert J. (2002). "Congenital erythropoietic porphyria: identification and expression of eight novel mutations in the uroporphyrinogen III synthase gene". British Journal of Haematology. 117 (4): 980–987. doi:10.1046/j.1365-2141.2002.03558.x. ISSN 0007-1048. PMID 12060141.
  17. ^ Brendan Colby. Outsmart Your Genes: How Understanding Your DNA Will Empower You to Protect Yourself Against Cancer, Alzheimer's, Heart Disease, Obesity, and Many Other Conditions. Penguin, 2010. ISBN 0399535578
  18. ^ Andrea Hoffmann and Panagiotis A Tsonis. Book Review: Outsmart Your Genes Human Genomics 2011, 5:516-517
  19. ^ "Show Synopsis". Thedoctorstv.com. Archived from the original on 2011-04-26. Retrieved 2011-06-01.
  20. ^ Kelly, Megyn. A look at the story of Taylor Muhl. Today (Feb 23, 2018), https://www.proquest.com/other-sources/look-at-story-taylor-muhl/docview/2008176519/se-2 (accessed July 19, 2024).

Further reading

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