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Adenosine nucleosidase

From Wikipedia, the free encyclopedia
adenosine nucleosidase
Identifiers
EC no.3.2.2.7
CAS no.9075-41-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, an adenosine nucleosidase (EC 3.2.2.7) is an enzyme that catalyzes the chemical reaction

adenosine + H2O D-ribose + adenine

Thus, the two substrates of this enzyme are adenosine and H2O, whereas its two products are D-ribose and adenine.

This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is adenosine ribohydrolase. Other names in common use include adenosinase, N-ribosyladenine ribohydrolase, adenosine hydrolase, and ANase. This enzyme participates in purine metabolism.

References

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  • MAZELIS M, CREVELING RK (1963). "AN ADENOSINE HYDROLASE FROM BRUSSELS SPROUTS". J. Biol. Chem. 238: 3358–61. PMID 14085386.