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Acrylyl-CoA reductase (NADPH)

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Acrylyl-CoA reductase (NADPH)
Identifiers
EC no.1.3.1.84
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Acrylyl-CoA reductase (NADPH) (EC 1.3.1.84) is an enzyme with systematic name propanoyl-CoA:NADP+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

propanoyl-CoA + NADP+ acryloyl-CoA + NADPH + H+

This enzyme catalyses a step in the 3-hydroxypropionate/4-hydroxybutyrate cycle, an autotrophic CO2 fixation pathway found in some Thermoacidophilic archaea.

References

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  1. ^ Berg IA, Kockelkorn D, Buckel W, Fuchs G (December 2007). "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea". Science. 318 (5857): 1782–6. doi:10.1126/science.1149976. PMID 18079405.
  2. ^ Teufel R, Kung JW, Kockelkorn D, Alber BE, Fuchs G (July 2009). "3-hydroxypropionyl-coenzyme A dehydratase and acryloyl-coenzyme A reductase, enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle in the Sulfolobales". Journal of Bacteriology. 191 (14): 4572–81. doi:10.1128/JB.00068-09. PMC 2704735. PMID 19429610.
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