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Abikoviromycin

From Wikipedia, the free encyclopedia
Abikoviromycin
Names
IUPAC name
(1S,3R,10Z)-10-ethylidene-2-oxa-6-azatricyclo[5.3.0.01,3]deca-6,8-diene[1]
Other names
Latumcidin
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C10H11NO/c1-2-7-3-4-8-10(7)9(12-10)5-6-11-8/h2-4,9H,5-6H2,1H3/b7-2-/t9-,10+/m1/s1
    Key: KQSFHAWSULOGRI-LPPIIHRRSA-N
  • CC=C1C=CC2=NCCC3C12O3
Properties
C10H11NO
Molar mass 161.204 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Abikoviromycin is an antiviral antibiotic piperidine alkaloid with the molecular formula C10H11NO which is produced by the bacteria Streptomyces abikoensis and Streptomyces rubescens.[2][1][3][4]

References

[edit]
  1. ^ a b "Abikoviromycin". Pubchem.ncbi.NLM.nih.gov.
  2. ^ Wørmer, Gustav J.; Poulsen, Thomas B. (April 2022). "The [4.3.0] Piperidine Alkaloids: Architectures, Biology, Biosyntheses, and the Complete Details of the Asymmetric Syntheses of Streptazone A and Abikoviromycin". Synlett. 33 (7): 637–654. doi:10.1055/a-1688-0826. S2CID 243842986.
  3. ^ Ph.D, DR ANTHONY MELVIN CRASTO (27 March 2019). "Abikoviromycin". New Drug Approvals.
  4. ^ Gurevich, A.I.; Kolosov, M.N.; Korobko, V.G.; Onoprienko, V.V. (January 1968). "The structure of abikoviromycin". Tetrahedron Letters. 9 (18): 2209–2212. doi:10.1016/S0040-4039(00)89721-X. PMID 5651005.

Further reading

[edit]
  • Wørmer, Gustav J.; Villadsen, Nikolaj L.; Nørby, Peter; Poulsen, Thomas B. (3 May 2021). "Concise Asymmetric Syntheses of Streptazone A and Abikoviromycin". Angewandte Chemie International Edition. 60 (19): 10521–10525. doi:10.1002/anie.202101439. PMID 33576128.