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4-Methylphenmetrazine

From Wikipedia, the free encyclopedia
4-Methylphenmetrazine
Identifiers
  • 3-methyl-2-(4-methylphenyl)morpholine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC12H17NO
Molar mass191.274 g·mol−1
3D model (JSmol)
  • CC1C(OCCN1)C2=CC=C(C=C2)C
  • InChI=1S/C12H17NO/c1-9-3-5-11(6-4-9)12-10(2)13-7-8-14-12/h3-6,10,12-13H,7-8H2,1-2H3
  • Key:NWNCIXFIIDVRKE-UHFFFAOYSA-N

4-Methylphenmetrazine (mephenmetrazine, 4-MPM, PAL-747) is a recreational designer drug with stimulant effects. It is a substituted phenylmorpholine derivative, closely related to better known drugs such as phenmetrazine and 3-fluorophenmetrazine. It was first identified in Slovenia in 2015,[1][2] and has been shown to act as a monoamine releaser with some preference for serotonin release.[3][4]

See also

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References

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  1. ^ "Analytical Report. 4-MPH (C12H17NO) 3-methyl-2(p-tolyl)morpholine" (PDF). National Forensic Laboratory. Slovenia. 14 October 2015.
  2. ^ "Europol 2015 Annual Report on the implementation of Council Decision 2005/387/JHA" (PDF). The European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) & Europol.
  3. ^ US 20130203752, Blough BE, Rothman R, Landavazo A, Page KM, Decker AM, "Phenylmorpholines and analogues thereof", published 8 August 2013, issued 11 April 2017, assigned to National Institutes of Health, U.S. Department of Health and Human Services 
  4. ^ McLaughlin G, Baumann MH, Kavanagh PV, Morris N, Power JD, Dowling G, et al. (September 2018). "Synthesis, analytical characterization, and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho- and meta- positional isomers". Drug Testing and Analysis. 10 (9): 1404–1416. doi:10.1002/dta.2396. PMC 7316143. PMID 29673128.