The 2000 Piedmontese regional election took place on 16 April 2000. Enzo Ghigo of Forza Italia (FI) was re-elected for the second time in a row as the president of Piedmont, defeating Livia Turco of the Democrats of the Left (DS). His re-election resulted in a landslide, as this time he was also supported also by Lega Nord (Northern League).
FI was confirmed as the largest party in the region with an historic 30.8% of the vote, while the DS were the second largest party with 17.7%. Piedmont was confirmed as a stronghold of Bonino List, whose leader Emma Bonino was candidate for president and took 5.7% of the vote.
Regional elections in Piedmont were ruled by the Tatarella law, which was approved in 1995 and provided for a mixed electoral system. Four fifths of the regional councilors were elected in provincial constituencies by proportional representation, using the largest remainder method with a Droop quota and open lists, while the residual votes and the unassigned seats were grouped into a single regional constituency, where the whole ratios and the highest remainders were divided with the Hare quota among the provincial party lists; one fifth of the council seats instead was reserved for regional lists and assigned with a majoritarian representation system, in which the leader of the regional list that scored the highest number of votes was elected to the presidency of the region, while the other candidates were elected regional councilors.
A threshold of 3% had been established for the provincial lists, which could still have entered the regional council if the regional list to which they were connected had scored at least 5% of valid votes. The panachage was also allowed; the voter can indicate a candidate for the presidency but prefer a provincial list connected to another candidate.