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File:Mechanisms of ZAP-mediated repression of viral gene expression.gif

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Summary

Description
English: ZAP binds to ZRE-containing viral RNA and, along with its cofactor TRIM25, can either (a) cause RNA degradation by interacting with the putative endonuclease KHNYN or (b) repress messenger RNA translation by inhibiting eIF4A and 4G
Date
Source https://www.annualreviews.org/content/journals/10.1146/annurev-virology-091919-104213
Author Chad Swanson

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Captions

ZAP binds to ZRE-containing viral RNA and, along with its cofactor TRIM25, can either (a) cause RNA degradation by interacting with the putative endonuclease KHNYN or (b) repress messenger RNA translation by inhibiting eIF4A and 4G

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15 June 2021

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