File:Finasteride Mechanism.png
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Summary
| Description |
English: This is the mechanism of inhibition for Finasteride on 5α-Reductase. Finasteride works to inhibit 5α-Reductase through competitive inhibition, which is why the mechanism shows the NADP+ getting attacked by the enolate formed rather than instant tautamerization occurring like in the case of 5α-Reductase's work on testosterone. Finasteride does eventually get released from 5α-Reductase enzyme-substrate complex which is why it is not considered a suicide inhibitor as the product eventually formed is dihydrofinasteride. |
| Date | |
| Source | Own work |
| Author | SJKH183 |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 07:40, 7 March 2021 | | 1,700 × 1,100 (186 KB) | SJKH183 | Uploaded own work with UploadWizard |
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